Publications by authors named "Vanessa Arreola"
Article Synopsis
- Scientists found that using a special protein called H1FOO-DD helps improve how well human cells can be turned into pluripotent stem cells, which can become any type of cell in the body.
- This method makes sure the new stem cells are more similar to each other and better at becoming different types of cells when needed.
- The research shows that a certain protein, FKBP1A, is important for this process to work effectively.
Naive human induced pluripotent stem cells (iPSCs) can be generated by reprogramming somatic cells with Sendai virus (SeV) vectors. However, only dermal fibroblasts have been successfully reprogrammed this way, and the process requires culture on feeder cells. Moreover, SeV vectors are highly persistent and inhibit subsequent differentiation of iPSCs.
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