Publications by authors named "Vanessa Aitken"
The synthesis and biological evaluation of brassinosteroids (BRs) analogs with chemical modification in the side alkyl chain is a matter of current interest. Recently, a series of BR analogs with phenyl or benzoate groups in the alkyl chain have been reported. The effect of substitution in the aromatic ring on the biological activities of these new analogs has been evaluated, and the results suggest that the bioactivity is enhanced by substitution with an F atom.
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- - The study focuses on examining whether the C22 configuration in brassinosteroids is crucial for their biological activity, particularly in analogs with a short side chain.
- - Researchers synthesized new brassinosteroid analogs with a 24-norcholane type side chain and explored different methods for dihydroxylation to determine the best reaction for achieving specific product ratios and yields.
- - Their findings show that Upjohn dihydroxylation yielded the most selective result, and all new compounds were fully characterized, contributing to the understanding of C22's significance in plant hormonal growth activity.