Rupatadine: global safety evaluation in allergic rhinitis and urticaria.

Introduction: Rupatadine is a second-generation H1-antihistamine with dual affinity for histamine H1 and PAF receptors. Rupatadine is indicated for the treatment of allergic rhinitis and urticaria.

Areas Covered: A Medline search was conducted to identify preclinical and clinical studies of rupatadine.

Safety evaluation of desloratadine in allergic rhinitis.

Introduction: Desloratadine is a biologically active metabolite of second-generation antihistamine loratadine. It is also indicated for the treatment of allergic diseases, including allergic rhinitis.

Areas Covered: A Medline search was conducted to identify preclinical and clinical studies of desloratadine.

Impact of sleep as a specific marker of quality of life in allergic rhinitis.

Allergic rhinitis (AR) is a common disorder, which represents a considerable burden both on individual patients and society. It is associated with bothersome symptoms, which may impair usual daily activities, sleep quality, and productivity. Associated with impaired sleep, quality of life is significantly impaired in AR patients.