Proteomes of Uropathogenic Growing in Human Urine and in J82 Urinary Bladder Cells.

Uropathogenic (UPEC) are the most common cause of urinary tract infection (UTI). UPEC normally reside in the intestine, and during establishment of UTI, they undergo metabolic adaptations, first to urine and then upon tissue invasion to the bladder cell interior. To understand these adaptations, we used quantitative proteomic profiling to characterize protein expression of the UPEC strain UTI89 growing in human urine and when inside J82 bladder cells.

Genomic Analysis of Antimicrobial Resistance and Resistance Plasmids in Serovars from Poultry in Nigeria.

Antimicrobial resistance is a global public health concern, and resistance genes in , especially those located on mobile genetic elements, are part of the problem. This study used phenotypic and genomic methods to identify antimicrobial resistance and resistance genes, as well as the plasmids that bear them, in isolates obtained from poultry in Nigeria. Seventy-four isolates were tested for susceptibility to eleven commonly used antimicrobials.