Starling resistor vs. distensible vessel models for embolic pulmonary hypertension.

We investigated whether the Starling resistor model (Mitzner et al. J. Appl.

[Aspects of pathological physiology of the dog in extracorporeal circulation].

During ECC, dogs ventilate spontaneously according to classical physiology. Further, given the CO2 clearance insured by the ECC oxygenator, many hours of reversible apnea are tolerated without sequellae. Surgical removal of the lungs shows that an emptied chest still responds to chemical drives, but the absent lung-recoil causes hyperinflation with lethal failure.

Postoperative radiotherapy after pneumonectomy: impact of modern treatment facilities.

Purpose: The present study was undertaken to see how modern treatment facilities, computed tomography (CT)-based treatment planning and linear accelerator, have modified the results of postoperative irradiation after a pneumonectomy for lung cancer.

Methods And Materials: Between 1970-1985, 103 patients were treated in our department after a pneumonectomy: 50 patients with a T1T2N0 tumor and 53 patients with a T3, N1 or N2 tumor. Three groups were considered: 27 patients had only surgical resection, 51 patients were irradiated postoperatively with a Co60 source, and 25 patients were treated using those modern facilities.

Embolus size affects gas exchange in canine autologous blood clot pulmonary embolism.

Embolic pulmonary hypertension is associated with alterations in gas exchange of variable severity, which we hypothesized to be related to embolus size. We therefore examined the effects of different-size autologous blood clot embolization on pulmonary arterial pressure-cardiac output relationships (Ppa/Q) and on the distribution of ventilation-perfusion ratios (VA/Q) in 18 intact anesthetized and ventilated (inspired fraction of O2 0.4) dogs.

[Treatment of breastplate deformities: assessment using CT scanning and functional tests].

A study to evaluate both the pre- en postoperative functional and morphologic status of major anterior chest wall deformities. Four of the eight patients suffered from a progressive reduction in physical capabilities. Preoperative pulmonary function tests demonstrated restriction in pulmonary function.

Effects of embolus size on hemodynamics and gas exchange in canine embolic pulmonary hypertension.

We examined the effects of different-sized glass-bead embolization on pulmonary hemodynamics and gas exchange in 12 intact anesthetized dogs. Pulmonary hemodynamics were evaluated by multipoint pulmonary arterial pressure (Ppa)/cardiac output (Q) plots before and 60 min after sufficient amounts of 100-microns (n = 6 dogs) or 1,000-microns (n = 6 dogs) glass beads to triple baseline Ppa were given and again 20 min after 5 mg/kg hydralazine in all the animals. Gas exchange was assessed using the multiple inert gas elimination technique in each of these experimental conditions.

Bronchiolar morphology after systemic arterial interruption.

To assess ischemic lesions as a factor in obliterative bronchiolitis after lung transplantation, the authors severed the left bronchial arteries of 15 dogs, together with the left stem bronchus, the latter being immediately reanostomosed. They examined the bronchioles at weekly interfals up to three and a half months. On the week chosen each dog was anesthetized, totally heparinized, and exsanguino-perfused with saline.

Effort rupture of the diaphragm.

Effort rupture of the diaphragm is rare and accounts for only 1% of all diaphragmatic injuries. A 23 year old patient with bilateral rupture that followed sudden movement is described.

Penetration of aminoglycosides in uninfected pleural exudates and in pleural empyemas.

The concentrations of gentamicin, netilmicin, and amikacin were determined after one single intravenous injection in uninfected pleural fluid after thoracotomy and in purulent pleural empyemas. The mean peak concentrations in the pleural fluid after the injection of gentamicin (1.5 mg/kg), netilmicin (2.

Hypophosphatemia after cardiothoracic surgery.

The incidence of hypophosphatemia during the first 48 h following cardiothoracic surgery was prospectively studied in 74 patients. Hypophosphatemia, defined by a serum phosphate below 2.50 mg/dl, was observed in 19 of 34 (56%) patients after thoracic surgery and in 20 of 40 (50%) patients after cardiac surgery.

[Significance of cardiopulmonary resuscitation in thoracic surgery].

45 patients admitted in the thoracic non-cardiac surgery service of the U.L.B.

Cardiac tamponade following penetrating thoracic trauma: unusual evolution.

We report a case of cardiac tamponade following a penetrating wound of the heart treated surgically. The patient developed later on a pericarditis of the immunologic type complicated by new tamponade. The clinical situation was only relieved by corticotherapy.

Phrenic nerve function after pneumonectomy.

Using surface electrodes over the lower chest wall, we measured the phrenic nerve conduction time, ie, the time interval between the stimulation of the phrenic nerve in the neck and the onset of the diaphragmatic muscle action potential, in ten patients who had undergone pneumonectomy several years before (mean, eight years) and in 31 control subjects (bilaterally in 19 of them). The mean (+/- SD) value in the control subjects was 7.0 (+/- 0.