Publications by authors named "Vanden Lamar Grube"
Am J Dermatopathol
July 2023
Article Synopsis
- - Squamoid eccrine ductal carcinoma (SEDC) is a rare and underrecognized sweat gland cancer that poses risks for local recurrence and metastasis, with a distinct biphasic differentiation pattern resembling well-differentiated cutaneous squamous cell carcinoma (cSCC) and infiltrative ductal specificity.
- - Diagnosis relies solely on histopathologic examination, and while its development remains poorly understood, a genetic analysis through whole-exome sequencing has identified multiple mutations that overlap with those found in cSCC but differ from other sweat gland cancers.
- - The findings suggest that SEDC may start as a well-differentiated cSCC before evolving into a sweat gland-like tumor, highlighting the need for
