Publications by authors named "Vandana Hegde"
Article Synopsis
- The study focuses on developing a rapid and accurate molecular detection system, called the PathCrisp assay, to identify infections and antibiotic resistance directly from culture samples.
- The PathCrisp assay uses a combination of loop-mediated isothermal amplification and CRISPR-based detection, showing high sensitivity and specificity, particularly in detecting the New Delhi metallo-beta-lactamase (NDM) gene in clinical samples.
- This novel assay provides results in about 2 hours without the need for complex equipment or extensive DNA purification, aiming to improve antibiotic treatment decisions in various healthcare settings.
Background: Infertility is a global burden and has become exceedingly common in the preceding years; controlled ovarian stimulation (COS) is a pre-requisite for couples opting to conceive via fertilisation (IVF). Based on the number of oocytes retrieved upon COS, a patient may be classified as a good responder or poor responder. The genetic aspect of response to COS has not been elucidated in the Indian population.
View Article and Find Full Text PDFIntroduction: Placental transfusion strategies in preterm newborns have not been evaluated in low- and middle-income countries (LMICs). The objective of this systematic review was to compare placental transfusion strategies in preterm newborns in LMICs, including delayed cord clamping (DCC) for various time intervals, DCC until cord pulsations stop, umbilical cord milking, and immediate cord clamping (ICC).
Methods: Medline, Embase, CINAHL, and CENTRAL were searched from inception.
Lin-7 targets the Kir 2.3 channel on the basolateral membrane via a L27 domain interaction with CASK.
Am J Physiol Cell Physiol
December 2007
Polarized expression of the Kir 2.3 channel in renal epithelial cells is influenced by the opposing activities of two different PDZ proteins. Mammalian Lin-7 (mLin-7) directly interacts with Kir 2.
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