Publications by authors named "Vandack Alencar Nobre Junior"
Droplet Digital PCR for Diagnosis in Bronchoalveolar Lavage Samples from Patients with Ventilator-Associated Pneumonia.
Mirna Giselle Moreira Anna Gabriella Guimarães Oliveira Ihtisham Ul Haq Tatiana Flávia Pinheiro de Oliveira Wadi B Alonazi Vandack Alencar Nobre Junior
Antibiotics (Basel)
September 2024
Article Synopsis
- Advanced diagnostic technologies like droplet digital PCR (ddPCR) provide a precise way to identify and measure pathogens in mini bronchoalveolar lavage samples for diagnosing ventilator-associated pneumonia (VAP).
- VAP is a serious lung infection in patients on ventilators, making accurate and timely diagnosis essential for effective treatment and reducing patient risk.
- The study found that ddPCR was more sensitive and able to detect pathogens in a higher percentage of clinical samples compared to traditional methods, while also avoiding issues with calibration curves.
Background: The aim of this study was to investigate the HCV genotypes, hepatic siderosis, inflammatory activity and fibrosis of the liver in patients with chronic renal failure (CRF) on haemodialysis in Brazil.
Methods: A cohort of 72 CRF patients was compared with a group of 65 candidates for blood donation (CBD). For the subjects selected, who tested positive for anti-HCV antibodies and were HCV-PCR positive, a protocol with epidemiological, clinical and laboratory information was completed.