Publications by authors named "Van Thi Thuy Nguyen"

HIV self-testing, which has been increasingly available since 2016, can substantially enhance the uptake of HIV testing, especially for key populations. Clinical trials have explored the application of self-testing in various HIV prevention strategies, including post-exposure prophylaxis (PEP), pre-exposure prophylaxis (PrEP), and voluntary medical male circumcision. Research indicates that self-testing can facilitate PrEP initiation and improve adherence and continuation.

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Introduction: In Viet Nam, key populations (KPs) face barriers accessing HIV services. Virtual platforms can be leveraged to increase access for KPs, including for HIV self-testing (HIVST). This study compares reach and effectiveness of a web-based HIVST intervention from pilot to scale-up in Viet Nam.

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Objective: Pre-exposure prophylaxis (PrEP) was introduced in Viet Nam in 2017, but data on oral PrEP preference and effective use beyond 3 months are limited. We aimed to evaluate PrEP preferences for PrEP, factors influencing uptake, choice and effective use, as well as barriers to PrEP.

Methods: This is a prospective cohort study in Can Tho, Viet Nam.

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Objective: HIV remains a significant burden, despite expanding HIV prevention tools. Long-acting injectable cabotegravir (CAB-LA) is a new preexposure prophylaxis (PrEP) product. We reviewed existing evidence to determine the efficacy and safety of CAB-LA as PrEP to inform global guidelines.

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Article Synopsis
  • Key populations at high risk for HIV and syphilis, such as sex workers and drug users, were studied to determine the health and economic benefits of different testing strategies using a dual rapid diagnostic test (RDT) in Vietnam.
  • Five testing scenarios were modeled over a 15-year period, revealing that annual testing with the dual RDT was the most cost-effective method, preventing numerous HIV and syphilis cases.
  • The findings suggest that implementing annual dual testing among these high-risk groups is an efficient approach to help meet global targets for reducing HIV and syphilis infections.
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Objective: Men with HIV are less likely than women to know their status, be on antiretroviral therapy, and be virally suppressed. This review examined men's community-based HIV testing services (CB-HTS) outcomes.

Design: Systematic review and meta-analysis.

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Article Synopsis
  • * While the World Health Organization (WHO) acknowledges that nurses can also provide HIV pre-exposure prophylaxis (PrEP), many countries lack the necessary policies to support this practice, especially in the Asia-Pacific region.
  • * There is a growing recognition among service providers that expanding access to PrEP requires nurse involvement, and countries that allow nurses to prescribe ART could set a precedent for broader implementation of nurse-led PrEP delivery.
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Introduction: Monitoring the population-level emergence and transmission of HIV drug resistance (HIVDR) is necessary for supporting public health programmes. This study provides a nationally representative prevalence estimate of HIVDR in people initiating antiretroviral therapy (ART) and estimates of acquired HIVDR and viral load (VL) suppression in people who have received it for 12 or ≥48 months in Vietnam.

Methods: The study was conducted between September 2017 and March 2018 following World Health Organization guidance.

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HIV self-testing has emerged as a safe and effective approach to increase the access to and uptake of HIV testing and treatment, especially for key populations. Applying self-testing to hepatitis C virus (HCV) may also offer an additional way to address low coverage of HCV testing and to accelerate elimination efforts. To understand the potential for HCV self-testing (HCVST), an observational study was conducted to assess the acceptability and usability of the OraQuick HCV Self-Test (prototype) among people who inject drugs (PWID) and men who have sex with men (MSM) in Thai Nguyen, a province in northern Vietnam.

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Pregnant women in Vietnam have a high prevalence of hepatitis B virus (HBV) and low prevalence of human immunodeficiency virus (HIV) and syphilis. This study aims to assess the feasibility and benefit of universal testing for HIV, HBV and syphilis in antenatal care (ANC) services. A pilot project was conducted in the Thai Nguyen province of Vietnam between 2012 and 2014.

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Article Synopsis
  • The HIV epidemic in Vietnam primarily affects key populations, such as people who inject drugs, men who have sex with men, and sex workers, who have limited access to traditional HIV testing services.
  • To improve testing rates, community-driven approaches like lay provider and self-testing, alongside assisted partner notification (aPN), were implemented starting in 2017.
  • From January 2017 to May 2018, nearly 4,000 individuals were tested, with more than 94% of those who were HIV-positive starting antiretroviral therapy, demonstrating the effectiveness of these community-based strategies.
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Introduction: In Vietnam, HIV testing services had been available only at provincial and district health facilities, but not at the primary health facilities. Consequently, access to HIV testing services had been limited especially in rural areas. In 2012, Vietnam piloted decentralization and integration of HIV services at commune health stations (CHSs).

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Background: Vietnam has a concentrated HIV epidemic with injection drug use being the dominant mode of HIV transmission. Vietnam has rapidly expanded antiretroviral therapy (ART) and methadone maintenance therapy (MMT). This study aims to analyze ART uptake and retention among male clients receiving MMT in Vietnam in the early phase of the MMT program.

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The evidence for the efficacy of walking in reducing the risk of and preventing coronary heart disease (CHD) is not completely understood. This meta-analysis aimed to quantify the dose-response relationship between walking and CHD risk reduction for both men and women in the general population. Studies on walking and CHD primary prevention between 1954 and 2007 were identified through Medline, SportDiscus and the Cochrane Database of Systematic Reviews.

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Background: Hepatitis B virus (HBV) is the major cause of chronic liver disease in Vietnam. This study aimed to estimate and project chronic HBV prevalence and HBV-related liver cirrhosis (LC) and hepatocellular carcinoma (HCC) for the period 1990-2025.

Method: The Vietnamese population for the period 1990-1999 was derived from census data to 1999 and from 2000 to 2025 based on projection data from the United States Census Bureau.

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Article Synopsis
  • In northern Vietnam, a study was conducted to assess the prevalence of hepatitis C virus (HCV) infection in a rural population, finding a low prevalence rate of 1.0%.
  • The study identified certain risk factors, such as hospital admissions and having tattoos, as significant predictors of HCV infection, while farmers showed lower rates of infection compared to other occupations.
  • The findings suggest a need to enhance infection control measures in healthcare facilities and other environments to reduce HCV transmission in the community.
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Article Synopsis
  • Hepatitis B is a significant health issue in rural Vietnam, with a study conducted on 837 participants revealing a 19% prevalence of active HBV infection and 1.3% for HDV.
  • Key risk factors for HBV infection include being over 60, residing in Vu Thu district, hospital admissions, acupuncture history, and practices like syringe reuse and razor sharing.
  • The findings highlight the need for improved infection control in healthcare settings as HBV infections are common and often lead to elevated liver enzyme levels in affected individuals.
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Background And Aim: Australia has increasing immigration from hepatitis B virus (HBV) endemic countries of the Asia-Pacific region (APR). This study estimates immigration-related chronic HBV cases, chronic HBV prevalence, and HBV-related hepatocellular carcinoma (HCC) from 1960 to 2005 and projects HBV-related HCC to 2025 in Australia among people born in the APR.

Methods: The populations of APR origin for the period 1960-2005 were derived from Australian census data.

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