NLRP3 inflammasome activation contributes to the development of the pro-fibrotic phenotype of lung fibroblasts.

Idiopathic pulmonary fibrosis (IPF) is an irreversible progressive interstitial lung disease of unknown cause. The poorly understood pathophysiology of IPF poses substantial challenges to the development of effective anti-lung fibrotic drugs. The NLRP3 inflammasome, a key component of the innate immune system, has recently been linked to the pathogenesis of lung fibrosis.

Unveiling the role of heterophase nanostructure in MnO-based colorimetric sensors for ascorbic acid detection.

Nanozymes based on manganese oxide (MnO) are demonstrated to be promising probes in colorimetric sensing applications. In this study, the r-MnO/β-MnO heterophase nanostructure was simply prepared by a calcination process with controllable temperature. The characterization of the nanostructured material was confirmed by SEM, UV-vis spectroscopy, Raman, TGA-DSC, and XRD analysis.

Evaluating lecturer performance in Vietnam: An application of fuzzy AHP and fuzzy TOPSIS methods.

Higher education is regarded as being of paramount importance in Vietnam and as being essential to raising the level of the country's labor force and promoting economic progress. Evaluation of lecturers is one of the institution's activities and a crucial component of managing human resources in higher education institutions. How to evaluate faculty members' overall performance using a range of criteria is one of the key evaluation-related challenges.

Optimization of Multiplex-PCR Technique To Determine Azf Deletions in infertility Male Patients.

Background: To optimize the multiplex polymerase chain reaction (M-PCR) technique to diagnose microdeletions of azoospermia factors (AZF) on the Y chromosome and initially apply the technique to diagnose male patients with sperm density less than 5×10 million sperm/mL was assigned to do a test to check for AZF microdeletions on the Y chromosome.

Methods: Based on the positive control samples which belong to male subjects who have had 2 healthy children without any assisted reproductive technologies, the M-PCR method was developed to detect simultaneously and accurately AZF microdeletions on 32 male patients with sperm densities below 5×10 million sperm/mL of semen at the Department of Biology and Medical Genetics - Vietnam Military Medical University.

Results: Successful optimization of the M-PCR technique including 7 reactions arranged according to each AZFabc region using 24 STS/gene on the Y chromosome.

Electric-Field-Assisted Synthesis of Cu/MoS Nanostructures for Efficient Hydrogen Evolution Reaction.

Molybdenum sulfide-oxide (MoS, MS) emerges as the prime electrocatalyst candidate demonstrating hydrogen evolution reaction (HER) activity comparable to platinum (Pt). This study presents a facile electrochemical approach for fabricating a hybrid copper (Cu)/MoS (CMS) nanostructure thin-film electrocatalyst directly onto nickel foam (NF) without a binder or template. The synthesized CMS nanostructures were characterized utilizing energy-dispersive X-ray spectroscopy (EDS), scanning electron microscopy (SEM), X-ray diffraction (XRD), and electrochemical methods.

Mimosa pudica L. extract ameliorates pulmonary fibrosis via modulation of MAPK signaling pathways and FOXO3 stabilization.

Ethnopharmacological Relevance: Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing pulmonary disorder that has a poor prognosis and high mortality. Although there has been extensive effort to introduce several new anti-fibrotic agents in the past decade, IPF remains an incurable disease. Mimosa pudica L.

The evolutionary phylodynamics of human parechovirus A type 3 reveal multiple recombination events in South Korea.

Human parechovirus A (HPeV-A) is a causative agent of respiratory and gastrointestinal illnesses, acute flaccid paralysis encephalitis, meningitis, and neonatal sepsis. To clarify the characteristics of HPeV-A infection in children, 391 fecal specimens were collected from January 2014 to October 2015 from patients with acute gastroenteritis in Seoul, South Korea. Of these, 221/391 (56.

Predictors of twin pregnancy in in vitro fertilization with intracytoplasmic sperm injection cycles with day 3 double embryo transfer.

Objective: The purpose of this study was to identify factors associated with twin pregnancy following day 3 double embryo transfer (DET).

Methods: This retrospective cohort study incorporated data from 16,972 day 3 DET cycles. The participants were women aged between 18 and 45 years who underwent in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI) at My Duc Assisted Reproduction Technique Unit (IVFMD), My Duc Hospital, located in Ho Chi Minh City, Vietnam.

High-Throughput Manufacturing of Multimodal Epidermal Mechanosensors with Superior Detectability Enabled by a Continuous Microcracking Strategy.

Non-invasive human-machine interactions (HMIs) are expected to be promoted by epidermal tactile receptive devices that can accurately perceive human activities. In reality, however, the HMI efficiency is limited by the unsatisfactory perception capability of mechanosensors and the complicated techniques for device fabrication and integration. Herein, a paradigm is presented for high-throughput fabrication of multimodal epidermal mechanosensors based on a sequential "femtosecond laser patterning-elastomer infiltration-physical transfer" process.

Magnetoplasmonic photonic arrays for rapid and selective colorimetric detection of chloride ions in water.

The rapid and efficient detection of chloride (Cl) ions is crucial in a variety of fields, making the development of advanced sensing methods such as colorimetric sensors an imperative advancement in analytical chemistry. Herein, a novel, selective, and straightforward paper-based colorimetric sensing platform has been developed utilizing an amorphous photonic array (APA) of magnetoplasmonic Ag@FeO nanoparticles (MagPlas NPs) for the detection of Cl in water. Taking advantage of the highly responsive APA, the key principle of this sensing method is based on the chemical reaction between Ag and Cl, which results in the precipitation of high-refractive index (RI) AgCl.

Economic burden of Thalassemia treatment: An analysis from the Vietnam Social Security perspective.

Objectives: Thalassemia is a genetic disorder that significantly impacts the health and well-being of individuals in Vietnam. This study aimed to assess the economic burden of Thalassemia treatment in Lam-Dong Province from the perspective of the Vietnam Social Security and to develop a model to forecast these costs.

Methods: This study analyzed the medical records of all 288 health-insured Thalassemia patients who received treatment in Lam-Dong Province from 2019-2021.

Model of implementing proficiency testing in Vietnam, a developing country.

Backgrounds And Aims: The aim of this study is to provide a good approach for a quantitative EQA scheme assigned value with limited resources.

Materials And Methods: Twelve lyophilized EQA items were distributed to participants in 2021 from North to Southeast Vietnam to measure the concentration of nine parameters, including glucose, urea, creatinine, cholesterol, triglyceride, uric acid, AST, ALT, and GGT. The consensus value of the expert group and all participants were calculated and statistically compared to choose the most appropriate consensus value.

Assessing the robustness of COVID-19 vaccine efficacy trials: systematic review and meta-analysis, January 2023.

BackgroundVaccines play a crucial role in the response to COVID-19 and their efficacy is thus of great importance.AimTo assess the robustness of COVID-19 vaccine efficacy (VE) trial results using the fragility index (FI) and fragility quotient (FQ) methodology.MethodsWe conducted a Cochrane and PRISMA-compliant systematic review and meta-analysis of COVID-19 VE trials published worldwide until 22 January 2023.

Electron Detachments of NbSi ( = 1-3) Clusters from Density Matrix Renormalization Group-CASPT2 Calculations.

The electronic states of NbSi ( = 1-3) clusters have been explored using the state-of-the-art DMRG-CASPT2 method with relatively large active spaces. The leading configurations, bond distances, vibrational frequencies, and relative energies of the low-lying states were identified. Electron detachment energies of the anionic cluster and ionization energies of the neutral clusters were reported at the DMRG-CASPT2 level.

Environmentally Friendly Plastic Boats - A Facile Strategy for Cleaning Oil Spills on Water with Excellent Efficiency.

In this report, we demonstrate a novel plastic boat capable of selectively and efficiently collecting spilled oils while floating on water. The boat has macroscopic openings in its vertical and curved sidewalls. It is easily, quickly, and inexpensively fabricated using an environmentally friendly polymer via a three-dimensional printing technique.

Unveiling the effect of crystallinity and particle size of biogenic Ag/ZnO nanocomposites on the electrochemical sensing performance of carbaryl detection in agricultural products.

In this study, bio-Ag/ZnO NCs were synthesized a microwave-assisted biogenic electrochemical method using mangosteen () peel extract as a biogenic reducing agent for the reduction of Zn and Ag ions to form hybrid nanoparticles. The as-synthesized NC samples at three different microwave irradiation temperatures ( , , ) exhibited a remarkable difference in size and crystallinity that directly impacted their electrocatalytic behaviors as well as electrochemical sensing performance. The obtained results indicate that the sample showed the highest electrochemical performance among the investigated samples, which is attributed to the improved particle size distribution and crystal microstructure that enhanced charge transfer and the electroactive surface area.

Coastal landscape classification using convolutional neural network and remote sensing data in Vietnam.

The length of global coastline is about 356 thousand kilometers with various dynamic natural and anthropogenic. Although the number of studies on coastal landscape categorization has been increasing, it is still difficult to distinguish precisely them because the used methods commonly are traditional qualitative ones. With the leverage of remote sensing data and GIS tools, it helps categorize and identify a variety of features on land and water based on multi-source data.

Influences of Material Selection, Infill Ratio, and Layer Height in the 3D Printing Cavity Process on the Surface Roughness of Printed Patterns and Casted Products in Investment Casting.

As 3D-printed (3DP) patterns are solid and durable, they can be used to create thin wall castings, which is complicated with wax patterns because of the wax's fragility and high shrinkage ratio. According to this study's experiment results, polylactic acid (PLA), polyvinyl butyral (PVB), and castable wax (CW) are suitable materials for preparing investment casting (IC) cavities. The results indicate that the casting product with the highest-quality surface is obtained using a cavity prepared using a CW-printed pattern.

Large-scale Vietnamese point-of-interest classification using weak labeling.

Point-of-Interests (POIs) represent geographic location by different categories (e.g., touristic places, amenities, or shops) and play a prominent role in several location-based applications.

Structurally Diverse Bench-Stable Nickel(0) Pre-Catalysts: A Practical Toolkit for In Situ Ligation Protocols.

A flurry of recent research has centered on harnessing the power of nickel catalysis in organic synthesis. These efforts have been bolstered by contemporaneous development of well-defined nickel (pre)catalysts with diverse structure and reactivity. In this report, we present ten different bench-stable, 18-electron, formally zero-valent nickel-olefin complexes that are competent pre-catalysts in various reactions.

A new integrated circular economy index and a combined method for optimization of wood production chain considering carbon neutrality.

The wood industry is potentially advantageous to applying the concepts of circular economy for sustainable development and can contribute to the commitment of carbon neutrality. This study developed an integrated circular economy index based on five different quantitative indicators for assessment of the wood production chain: heat recovery rate, CO sequestration rate, fossil fuel substitution rate, renewable electricity usage rate, and revenue increase from the by-products. A combination of best-worst method (BWM) and linear goal programming (LGP) techniques was investigated to develop an optimal circular economy model of wood processing chain for reduction in CO emission.

Electrochemical Investigation of Porosity in Core-Shell Magnetoplasmonic Nanoparticles.

Porous core-shell nanoparticles (NPs) have emerged as a promising material for broad ranges of applications in catalysts, material chemistry, biology, and optical sensors. Using a typical Ag core-FeO shell NP, a.k.

Chirality of Fingerprints: Pattern- and Curvature-Induced Emerging Chiroptical Properties of Elastomeric Grating Meta-Skin.

Fingerprint-inspired elastomeric grating meta-skin (EGMS) is herein fabricated to investigate the chirality of fingerprints. The EGMS is made by a facile nanoimprinting method with a diffraction grating as a template using polydimethylsiloxane, followed by gold deposition. The chirality of the surface is caused by symmetry breaking, induced by the pattern () and curvature ().

Rapid Assembly of Magnetoplasmonic Photonic Arrays for Brilliant, Noniridescent, and Stimuli-Responsive Structural Colors.

There are usually trade-offs between maximizing the color saturation and brightness and minimizing the angle-dependent effect in structural colors. Here, a magnetic field-induced assembly for the rapid formation of scalable, uniform amorphous photonic arrays (APAs) featuring unique structural colors is demonstrated. The magnetic field plays a fundamental role in photonic film formation, making this assembly technology versatile for developing structural color patterns on arbitrary substrates.

One-Pot Synthesis of Magnetoplasmonic Au@FeO Nanowires: Bioinspired Bouligand Chiral Stack.

One-dimensional hybrid nanostructures composed of a plasmonic gold nanowire core covered by a shell of magnetic oxide nanoparticles (Au@FeO NWs) were synthesized by a one-pot solvothermal synthesis process. The effects of reaction temperature, time, reducing agent, and precursor as well as postsynthesis treatment were optimized to produce highly uniform NWs with a diameter of 226 ± 25 nm and a plasmonic core aspect ratio of 25 to 82. By exploiting the interaction of NWs with an external magnetic field, precise arrangements into highly periodic photonic structures were achieved, which can generate distinctive structural colors that are vividly iridescent and polarization-sensitive.