Publications by authors named "Van Pham"

The urban setting notwithstanding, rice cultivation prevails on the outskirts of Hanoi, with the burning of rice straw in the fields posing a significant challenge. Therefore, it is crucial to conduct spatial mapping of rice distribution, assess dry biomass, and determine emissions from rice straw burning within Hanoi city. The efficacy of the deep convolutional neural networks (DCNN) model has been evident in accurately mapping the spatial distribution of rice in Hanoi, where rice cultivation extensively thrives in suburban areas.

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OSBP ligands from the ORPphilin family are chemically complex natural products with promising anticancer properties. Here, we describe macarangin B, a natural racemic flavonoid selective for OSBP, which stands out from other ORPphilins due to its structural simplicity and distinct biological activity. Using a bioinspired strategy, we synthesized both (,,) and (,,)-macarangin B enantiomers, enabling us to study their interaction with OSBP based on their unique optical properties.

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Analysis of an antimicrobial extract from the agar-based culture of the marine-derived actinomycete Streptomyces sp. G666 led to the isolation of three new shikimic acid derivatives, streptomine A-C (1-3), along with five known compounds (4-8). Their structures were established by their spectral data analyses, including MS and NMR.

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Introduction: The role of afatinib in the first-line treatment of EGFR-mutant advanced non-small cell lung cancer (NSCLC) patients has been proven through clinical trials and real-world studies. However, additional data on the effectiveness of afatinib in patients with brain metastases are lacking.

Methods: EGFR-mutant NSCLC patients with brain metastases were retrospectively reviewed across nine cancer centers in Vietnam from April 1, 2018 to June 1, 2022.

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Purpose: To characterize the spectrum of uveitis in patients visiting three tertiary hospitals in Hanoi, Vietnam.

Methods: This study collected prospective and multicenter data from patients diagnosed with uveitis at three tertiary hospitals in Hanoi City, Vietnam, between January 2022 and January 2024. Data on age, sex, clinical and laboratory findings, and etiology were collected.

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VD20 broken rice, a byproduct of rice milling, shows significant potential for value-added applications, particularly in functional beverage production. This study investigates the impact of homogenization and pasteurization on the quality and stability of VD20 broken rice-based beverages. Homogenization at speeds 6000 to 12,000 rpm for 5 to 20 min improved product stability, while pasteurization between 80 and 95 °C for up to 20 min ensured microbial safety and extended shelf life.

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Article Synopsis
  • The study aimed to compare the clinical, radiological, and laboratory features of newly diagnosed smear-positive pulmonary tuberculosis in elderly patients (65+) versus younger patients in Vietnam.
  • Out of 183 patients analyzed, those aged 65 and older showed differences in symptoms and X-ray findings, with younger patients more likely to experience night sweats and cavitation lesions, while elderly patients experienced more muscle/joint pain and pulmonary fibrosis.
  • The research highlights the need for age-specific considerations in diagnosing and treating tuberculosis, indicating that tailored approaches could improve patient outcomes based on age-related differences.
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In this study, ultrasound waves were successfully applied to the osmosis process of dried dragon fruit products. Additionally, this study was aimed at determining the suitable parameters for the process of drying dragon fruit peels. The parameters including the size of slices (2-5 cm), blanching time (10-25 min), ultrasonic time (10-25 min), ultrasonic temperature (45°C-60°C), ultrasonic power (100-250 W), and drying temperature (45°C-60°C) were fully investigated.

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Introduction: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions. However, only a few studies have investigated the clinicodemographic and laboratory parameters predicting SJS and TEN outcomes other than mortality, such as severe complications or increased length of hospital stays. Our objectives are to identify admission risk factors predictive of severe complications and the accompanying clinical or biochemical markers associated with prolonged hospitalization.

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A simple grinding method using polyvinylpyrrolidone (PVP) as a capping agent is introduced to synthesize CoFeO nanoparticles. The effects of calcination temperature (ranging from 450 to 850 °C) on the structural, morphological, physical, and optical properties of the materials are investigated using various techniques, including thermogravimetric analysis/differential scanning calorimetry (TGA/DSC), powder X-ray diffraction (PXRD), transmission electron microscopy (TEM), N adsorption isotherm, ultraviolet-visible diffuse reflectance spectroscopy (UV-vis DRS), and vibrating sample magnetometry (VSM). The presence of PVP significantly suppresses the agglomeration of the materials, resulting in a nanocrystalline size of 18 nm for a sample calcined at 650 °C, which is approximately 38% smaller than that of the sample synthesized without PVP.

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Article Synopsis
  • - This phase 3 trial assessed the self-amplifying mRNA COVID-19 vaccine, ARCT-154, against the ChAdOx1-S adenovirus-vector vaccine in Vietnam, involving nearly 2,400 adult participants.
  • - Both vaccines had similar safety profiles, with mainly mild-to-moderate side effects and few serious adverse events reported.
  • - ARCT-154 showed higher neutralizing antibody responses and efficacy against COVID-19 compared to ChAdOx1-S, suggesting potential immunological advantages without compromising safety.
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A highly sensitive non-enzymatic absorption-based glucose sensor is introduced that combines ZnO nanorods with the ferrous oxidation-xylenol orange (FOX) assay. ZnO nanorods were successfully synthesized on the surface of a copper wire mesh, exhibiting high crystallinity, purity, and a large surface area. The glucose sensor displays a high sensitivity of 0.

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  • Anion exchange membrane water electrolysis (AEMWE) is a promising method for producing green hydrogen, as it can use cheaper, non-noble catalysts, but replacing expensive platinum (Pt) catalysts remains a challenge.
  • The study presents a new synthesis method for a ruthenium (Ru)-based catalyst that is much more efficient than existing Pt/C catalysts in alkaline conditions, demonstrating its effectiveness through various tests.
  • The two-step synthesis involves creating a nickel catalyst on carbon first, then depositing Ru evenly across its surface, resulting in lower voltage requirements (1.73 V at 1 A cm) and minimal precious metal usage (0.05 mg cm).
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  • Vermicelli production wastewater contains high levels of organic and nutrient pollutants, creating environmental challenges that conventional treatments struggle to manage efficiently.
  • A study tested the Fenton process coupled with aerobic activated sludge to improve the treatment of this wastewater, finding optimal conditions for maximum pollutant removal.
  • The integrated system showed promising results, achieving significant reductions in key parameters (like COD and BOD), but highlighted the need for further research to improve treatment efficiency, particularly due to the impact of high total dissolved solids (TDS).
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Background: Dioxin is an environmental pollutant as well as an endocrine disruptor in humans. Our longitudinal study wants to clarify the relationship between dioxin exposure and endocrine disorders in children living in the Vietnamese dioxin hotspot.

Method: Seventeen congeners of polychlorinated dibenzo-p-dioxins/polychlorinated dibenzo-furans (PCDDs/PCDFs) in maternal breast milk and seven serum steroid hormones in children of 43 and 46 mothers and their 9-year-old children from the non-exposure and the hotspot areas were measured, respectively.

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  • Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis are major causes of preventable bacterial meningitis in children, with vaccines available to combat these diseases.
  • A study was conducted in three pediatric hospitals in Vietnam from 2015 to 2018 to gather data on the impact of pneumococcal meningitis and its serotype distribution, which is important for the introduction of pneumococcal conjugate vaccines (PCVs).
  • Out of 1,803 suspected cases, 245 were confirmed as bacterial meningitis, with a high prevalence (93.5%) of cases caused by S. pneumoniae, predominantly from serotypes included in existing PCVs (most notably ser
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This study aimed to assess the presence of microplastics in bottom sediment and bivalve species, including Pinna bicolor, Atrina vexillum, Saccostrea sp., and Pinctada margaritifera, living in coral reefs on Vietnam's Southern coastal. The average microplastic abundance were 0.

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African swine fever (ASF), caused by the African swine fever virus (ASFV), is a deadly, highly contagious disease in both domestic pigs and wild boar. With mortality up to 100%, the disease has been making a serious impact on the swine industry worldwide. Because no effective antiviral treatment has been observed, proactive prevention such as vaccination remains the key to controlling the outbreak.

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Background: There is currently no validated tool available for assessing the potential significance of pharmacist interventions in Vietnam.

Aim: This study aimed to translate the CLEO tool from French into Vietnamese, validate the Vietnamese version, and demonstrate its feasibility in daily practice.

Method: The CLEO tool was translated into Vietnamese (CLEO) using a 5-step process by bilingual experts.

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Article Synopsis
  • Dynein cytoplasmic 1 light intermediate chain 1 (LIC1) is an important part of a motor complex in cells that helps move things around.
  • Scientists found a special zebrafish with a mutation in LIC1, which caused it to have more blood vessel growth (angiogenesis) than normal.
  • The research shows that LIC1 and certain helper proteins (RILPL1 and 2) are important because they help break down parts of the cell that can cause too much new blood vessel growth when damaged.
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This paper explores the relationship between lecturers' digital competence and the learning value of students in higher education. By conducting an empirical study with a sample of 626 lecturers, we validated the positive impact of the six dimensions of digital competence outlined in the DigCompEdu framework, including: (i) Professional engagement, (ii) Digital resources, (iii) Teaching and learning, (iv) Assessment, (v) Empowering learners, and (vi) Facilitating learners' digital competence on the student learning value. Our findings underscore the profound significance of these dimensions in shaping students' learning experiences and outcomes, particularly within the dynamic context of Industry 4.

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The emergence of multicancer early detection (MCED) tests holds promise for improving early cancer detection and public health outcomes. However, positive MCED test results require confirmation through recommended cancer diagnostic imaging modalities. To address these challenges, we have developed a consultation and work-up protocol for definitive diagnostic results post MCED testing, named SPOT-MAS.

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This article studies the problem of stabilizing a leader-follower formation specified by a set of bearing constraints while disturbed by some unknown uniformly bounded disturbances. A set of leaders are positioned at their desired positions while each follower is modeled by a single integrator with an additive time-varying disturbance. Adaptive variable-structure control laws using displacements or only bearing vectors are applied to stabilize the desired formation.

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A scanning acoustic microscopy (SAM) system is a common non-destructive instrument which is used to evaluate the material quality in scientific and industrial applications. Technically, the tested sample is immersed in water during the scanning process. Therefore, a robot arm is incorporated into the SAM system to transfer the sample for in-line inspection, which makes the system complex and increases time consumption.

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Dengue hemorrhagic fever (DHF) is the most prevalent and fastest-growing vector-borne disease globally, with symptoms ranging from mild to severe and, in some cases, fatal. Quang Nam province in Vietnam can serve as a model for dengue epidemiological study, as it is an endemic region for DHF with a tropical climate, which significantly constrains the health system. However, there are very few epidemiological and microbiological reports on Dengue virus (DENV) serotypes in this region due to the limited availability of advanced surveillance infrastructure.

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