Publications by authors named "Van Anh Thi Tran"
Impact of clinical pharmacist-led interventions on switching from intravenous-to-oral antibiotics in patients with infectious diseases at a Vietnamese hospital.
Tu Nhat Thien Nguyen Quynh Thi Huong Bui Van-Anh Thi Tran Nhu Quynh Tran Nhi Truc Y Nguyen Mai Thi Phuong Tran
Trop Med Int Health
August 2023
Article Synopsis
- The study aimed to assess how clinical pharmacist-led interventions impacted the transition from intravenous (IV) to oral (PO) antibiotics for hospitalized patients with infectious diseases.
- Researchers evaluated data from two periods: before the intervention (January to June 2021) and during the intervention (January to June 2022), focusing on patient characteristics and treatment outcomes.
- Results showed a significant increase in the switch rate from IV to PO antibiotics (44.4% to 67.8%) and appropriate conversions (43.8% to 67.5%), indicating that pharmacist involvement improved the transition process without affecting the length of hospital stays or treatment outcomes.
Aspidiatas C and D ( and ), two new spirostanol saponins, were isolated along with two known compounds, (25 )-spirost-5-en-3-yl -L-rhamnopyranosyl-(1→4)--L-rhamnopyranosyl-(1→4)-[-L-rhamnopyranosyl-(1→2)]--D-glucopyranoside (), (25 )-spirost-5-en-3-yl -L-rhamnopyranosyl-(1→4)--L-rhamnopyranosyl-(1→4)--D-glucopyranoside () from the whole plant of collected in Vietnam. The chemical structures were determined by HRESIMS, 1D- and 2D-NMR analysis, and comparison with published data. Compound exhibited potent cytotoxicity against MCF7, HepG2, SK-LU-1, and HT-29 human cancer cell lines with IC values ranging from 0.
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