Publications by authors named "Valsala Madhavan Nair Biju"

The current manuscript describes a validated, responsive and rapid spectrofluorimetric method for quantifying ondansetron (OND) in authentic form, spiked human plasma and dosage forms. This is the first reported fluorescence study of Ondansetron in Triton X 100 system. Various variables affecting fluorescence response were studied precisely and optimised.

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The present manuscript gives a detailed account of highly selective, validated and sensitive method for quantification of pirfenidone in its pharmaceutical dosage forms and spiked human urine. The developed method is relied on the systematic study of the fluorescence action of Pirfenidone in Tween - 80 micellar medium. The Pirfenidone exhibits strong fluorescence at λ 396 nm upon excitation at λ 318 nm in Tween -80 medium.

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A novel chelating resin for preconcentration of heavy metals from various seawater samples has been developed by condensing 1-amino-2-hydroxy-7-[(4-hydroxyphenyl)diazenyl] naphthalene-4-sulfonic acid (AHDNS) with formaldehyde (1:2 mole ratio) in the presence of oxalic acid as the catalyst. The resin thus obtained was used as a solid sorbent for the separation of divalent metal ions present at trace levels in seawater. The functionalized phenol (AHDNS) was characterized by spectral studies.

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Article Synopsis
  • A new, efficient LC-MS/MS method was developed for measuring melatonin levels in milk.
  • The method involves extracting samples using dichloromethane and purifying them with a solid-phase extraction cartridge before analysis.
  • Results showed the method is accurate (92.2% accuracy), precise (1.55% mean precision), and has a strong linear calibration range, making it suitable for examining melatonin in both market and human milk.
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