Optimization of a digital health intervention to enhance well-being among adolescent and young adult cancer survivors: Design and methods of the EMPOWER full factorial trial.

Adolescent and young adult cancer survivors (AYAs) experience clinically significant distress and have limited access to supportive care services. Interventions to enhance psychological well-being have improved positive affect and reduced depression in clinical and healthy populations and have not been routinely tested in AYA survivors. We are optimizing a web-based positive skills intervention for AYA cancer survivors called Enhancing Management of Psychological Outcomes With Emotion Regulation (EMPOWER) by: (1) determining which intervention components have the strongest effects on well-being and (2) identifying demographic and individual difference variables that mediate and moderate EMPOWER's efficacy.

Hyaluronic acid injections administered within two months prior to total knee arthroplasty increase the risk for periprosthetic joint infection.

Background: It remains unknown how timing of preoperative intra-articular knee hyaluronic acid (HA) injections impacts risk for developing postoperative periprosthetic joint infection (PJI) following total knee arthroplasty (TKA).

Methods: The PearlDiver Mariner database was utilized to identified patients undergoing primary TKA between 2015 and 2022 who received an HA injection without a corticosteroid injection within 12 months prior to surgery. The HA cohort was matched 1:1 to a control cohort undergoing no preoperative injections (corticosteroid or HA).

[MMLV reverse transcriptase, a relevant tool for molecular biology].

The reverse transcriptase of Moloney Murine Leukemia Virus (MMLV) is an enzyme that synthesizes DNA from an RNA template. Among reverse transcriptases, this enzyme is currently the most commonly used in molecular biology and diagnostics. Since its discovery, this viral protein has been extensively studied, shedding light on its structural and functional characteristics, and offering opportunities to optimize the catalytic performances for biotechnological applications.

A case report of hepatic inflammatory myofibroblastic tumor in a pediatric patient: diagnostic challenges and management strategies.

Purpose: The aim of this study is to present a case of inflammatory myofibroblastic tumor (IMT) of the liver in a 4-year-old girl. We will discuss the diagnostic challenges, the role of the radiologist in differential diagnosis, treatment modalities, and clinical outcomes.

Methods: A case report of a 4-year-old girl with IMT of the liver is presented.

Health status and morphometrics of Galápagos magnificent frigatebirds () determined by hematology, biochemistry, blood gas, and physical examination.

The magnificent frigatebird ( MFB) is a widely distributed seabird. It has breeding areas in the tropical Atlantic Ocean and the Pacific Ocean (extending along Central America up to Baja California) (Schreiber & Burger, 2001). The (MFB-Gal) subspecies is native to the Galápagos Islands.

Prognostic value of magnetic resonance enterography for children with Crohn's disease: A multicenter, multireader study.

Background: Paediatric Inflammatory Crohn's MRE Index (PICMI) is a multi-point index of intestinal inflammation (mucosal and transmural) for children with CD. The present study aims to assess whether PICMI at diagnosis may predict the course of CD and to test the inter-reader agreement.

Methods: CD children with a ≥ 1-year follow-up were retrospectively enrolled.

Trends and Epidemiology in Revision Total Knee Arthroplasty: A Large Database Study.

Background: As the volume of primary total knee arthroplasty (TKA) continues to grow, the clinical and financial burden of revision total knee arthroplasty (rTKA) is expected to increase. The purpose of this investigation was to characterize contemporary indications and complications for rTKA.

Methods: Patients undergoing rTKA between 2010 and 2021 were identified within an administrative claims database.

From Surviving to Thriving: Key Considerations for Weight Control Across Diverse Cancer Survivorship Populations.

Background: Obesity is a chronic, relapsing, progressive disease of excess adiposity that increases the risk of dying from at least 16 types of cancer. The prevalence of obesity has increased more rapidly in cancer survivors compared with the general population. Tailored weight management strategies are needed to improve prognosis and health outcomes in the growing population of cancer survivors.

Enhancing Physical and Cognitive Efficiency in Elderly Individuals at Risk for Dementia Using Whole-Body Electrostimulation: A Randomized Controlled Trial.

: The aim of this randomized controlled trial (RCT) was to assess the impact of a 12-week intervention of two 20-min sessions per week, combining aerobic exercise with whole-body electromyostimulation (WB-EMS), on physical and cognitive performance in the elderly. : A total of 61 participants (age = 71 ± 5.64 years), healthy or at risk for dementia, were randomly assigned to an experimental training group (ETG, n = 33) and a control group (CON, n = 28).

Kinesiological Rehabilitation in a Young Adult with Biceps Femoralis Arteriovenous Malformation: A Case Study.

: This case study involved a 24-year-old male with an arteriovenous malformation localized in the long head of the right biceps femoris muscle, with an anterior cruciate ligament injury. The aim was to assess the effects of a five-week kinesiological protocol, which included global postural re-education and strengthening exercises focused on knee stabilization. The effectiveness of the therapeutic intervention was evaluated using Gait Analysis, clinical examination, and the SF-36 questionnaire to assess the patient's quality of life.

Bone and vascular effects of magnesium supplements in CKD patients (the MagicalBone Pilot Study).

Background And Objective: The progression of chronic kidney disease (CKD) involves the development of alterations in mineral metabolism that are closely related to cardiovascular outcomes and bone disease. Hypomagnesemia is associated with more rapid progression of CKD and other comorbidities. Our objective was to analyze in CKD patients stages 3-4 the impact of the administration of magnesium (Mg) carbonate on bone mineral density (BMD) and hemodynamic changes associated with by vascular calcification (VC).

Bisphosphonate Use in Patients Who Have Osteoporosis Does Not Increase the Risk of Periprosthetic Fracture Following Total Knee Arthroplasty.

Background: The purpose of this study was to evaluate the effect of preoperative bisphosphonate use in patients who have osteoporosis on the risk of complications following primary total knee arthroplasty (TKA).

Methods: An administrative claims database was queried for patients who have osteoporosis undergoing primary TKA between 2010 and 2019 with a minimum of 2-year follow-up. Bisphosphonate-naive patients and bisphosphonate users, defined as patients who had a continuous prescription for bisphosphonates for a minimum of 6 months preoperatively, were matched 1:1 based on age, sex, and comorbidity burden.

The Oxente Chagas Bahia Project: evaluating the efficacy of a rapid diagnostic test and treatments for Chagas disease.

Chagas disease (CD), caused by Trypanosoma cruzi, is a life-threatening neglected anthropozoonosis primarily transmitted by triatomine bugs. Affecting an estimated 5.7 million people globally, CD has significant morbidity and mortality, particularly in Latin America.

Hydrogen Sulfide Modulates Astrocytic Toxicity in Mouse Spinal Cord Cultures: Implications for Amyotrophic Lateral Sclerosis.

Hydrogen sulfide (HS), a known inhibitor of the electron transport chain, is endogenously produced in the periphery as well as in the central nervous system, where is mainly generated by glial cells. It affects, as a cellular signaling molecule, many different biochemical processes. In the central nervous system, depending on its concentration, it can be protective or damaging to neurons.

Bridging Generations Through Movement: "How and Why" Intergenerational Programs Operate-A Systematic and Narrative Review.

Well-being and social interaction are among the primary goals to be achieved for the elderly. Intergenerational physical activity (PA) has gained increasing attention due to its potential to encourage PA and social interaction, providing both social and physical benefits to both younger and older individuals. This review aimed to gain a deeper understanding of the potential roles of PA in facilitating intergenerational interactions and provide practical insights.

No Difference in Postoperative Complications between Simultaneous and Staged, Bilateral Unicompartmental Knee Arthroplasty.

The optimal timing of contralateral surgery following unicompartmental knee arthroplasty (UKA) remains unknown. Therefore, the objective of this study was to examine the differences in postoperative complications in patients undergoing unilateral, simultaneous, and staged bilateral UKA.The PearlDiver administrative claims database was queried for patients undergoing UKA between 2015 and 2020.

Motivated information avoidance in an mHealth weight loss intervention: Associations between unmet behavioral goals and likelihood of viewing program messages.

Background: Program engagement is positively associated with improved outcomes in mobile health (mHealth) interventions, but little is known about which factors may increase or decrease the likelihood of participants viewing program messages. This study examined the association between daily behavioral goal achievement and likelihood of reading daily messages, and if this relationship is moderated by baseline depressive symptoms in an mHealth weight loss intervention.

Methods: Data come from a 12-week microrandomized pilot mHealth weight management trial that tested the effects of daily messages on behavioral goals among 52 young adults (78.

Identification of perceived sentences using deep neural networks in EEG.

. Decoding speech from brain activity can enable communication for individuals with speech disorders. Deep neural networks (DNNs) have shown great potential for speech decoding applications.

The Impact of Travel Distance on Patient-Reported Outcomes Following Primary Total Hip Arthroplasty.

Background: Total hip arthroplasties (THAs) are increasingly being performed at high-volume centers, causing some patients to travel further distances to receive care. Concerns remain that increased travel distance limits follow-up, which may impact outcomes and early return to the hospital. The purpose of this study is to evaluate the impact of travel distance on 90-day patient-reported outcomes (PROs) and 90-day complication rates.

[Perioperative management and fast track in knee arthroplasty].

Background: Knee arthroplasty is an established surgical treatment for advanced osteoarthritis of the knee. In view of the rising number of surgical procedures, increasing costs in the healthcare system with a parallel increase in patient age and comorbidities, an evidence-based perioperative management is gaining importance. Fast Recovery concepts comprise a range of evidence-based strategies for optimizing the perioperative course.

[The potential of wearable technology in knee arthroplasty].

Background: Wearable technology has developed rapidly in recent years and offers promising possibilities for supporting and optimizing orthopaedic procedures, especially pre- and postoperatively. The continuous monitoring and precise analysis of movement patterns, as well as the individual adaptation of rehabilitation processes are just some of the potential benefits of wearable technology. The aim of this paper is to evaluate the potential of wearable technology in knee arthroplasty and to provide an overview of the evidence that is currently available.