Countercurrent chromatography approach to palladium and platinum separation using aqueous biphasic system.

For the first time, widespread aqueous biphasic polymer-salt extraction system was applied for selective separation of Pd(II) and Pt(IV) from chloride technological solutions by countercurrent chromatography using a rotating coiled column (an analog of centrifugal extractor). The principle novelty of the proposed approach is the possibility of multistage extraction process and the needlessness to add any specific reagents for targeted metal binding. The results showed that the use of poly(ethylene glycol)-1500 (PEG-1500) as a stationary phase allows 96-100% of both Pd(II) and Pt(IV) to be recovered from chloride solutions containing copper and nickel.

High-resolution ICP-MS approach for characterization of magnetic nanoparticles for biomedical applications.

The potential of iron oxide-based nanoparticles (IONs) as theranostic agents is believed to be in a great part due to non-invasive diagnosis and therapeutic applications. However, there is still a lack of well-recognized methodology to assess bioresistance, hypotoxicity, reactivity toward pertinent biomolecules, as well as an eventual dose of IONs as prerequisites for their clinical use. In this study, we demonstrate how application of high-resolution ICP-MS in combination with conventional ultrafiltration can address these important issues in a simple and high-throughput way.

Fractionation and characterization of nano- and microparticles in liquid media.

Submicron and micron particles present in liquid environmental, biological, and technological samples differ in their dimensions, shape, mass, chemical composition, and charge. Their properties cannot be reliably studied unless the particles are fractionated. Synthetic particles applied as components of analytical systems may also need preliminary fractionation and investigation.