Publications by authors named "Valery I Vechorko"
Clinical and pharmacogenetic features of patients with upper gastrointestinal lesions at a multidisciplinary hospital: the role of nonsteroidal anti-inflammatory drugs.
Natalia P Denisenko Anna S Zhiryakova Ivan V Sychev Alexander V Kryukov Svetlana N Tuchkova Valery I Vechorko
Drug Metab Pers Ther
June 2024
Objectives: Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly prescribed medications, but their use can be associated with a number of adverse reactions, including upper gastrointestinal lesions. The aim of the study was to identify clinical and pharmacogenetic factors associated with upper gastrointestinal lesions, including those linked to NSAIDs, in patients at a multidisciplinary hospital.
Methods: The study included 92 patients (mean age 59.
Article Synopsis
- The review discusses the potential benefits and drawbacks of using HIF prolyl hydroxylase inhibitors as a treatment option for COVID-19.
- These inhibitors can enhance the production of erythropoietin (Epo), which has anti-inflammatory and healing effects, possibly helping patients with moderate to severe symptoms.
- However, while they may address complications arising from the disease, they are not expected to be effective in preventing the initial stages of COVID-19 infection.