Systemic lupus erythematosus, Sjögren's syndrome and glomerular nephritis.

The combination of systemic lupus erythematosus, Sjögren's disease and severe diffuse glomerular nephritis has only rarely been reported. A 14-year-old girl is described with lupus nephritis in whom co-existent clinical and histological features of Sjögren's syndrome were found. These include bilateral parotid enlargement, xerostomia, increased serum amylase, reduced salivary secretion and lymphocyte infiltration of both salivary glands and kidneys.

Effects of lower body negative pressure (LBNP) on the distribution of body fluids.

Reduction of pressure on the lower part of the human body is believed to be capable of altering the normal fluid distribution. This could serve as a therapeutic method for emergency relief of the effects of hypertension, or it could be used as counterbalance for zero gravity and assist in preparing astronauts for reentry into the gravitational field. The present work describes a technique of assessment of the fluid shift caused by such pressure reduction.

Postpartum haemolytic-uraemic syndrome.

In a young woman a twin pregnancy and uneventful labour were complicated by the development of the postpartum haemolytic-uraemic syndrome. A number of unusual features of this syndrome were present, including early onset, accompanying hepatocellular necrosis, hepatic encephalopathy and bleeding diathesis. Early institution of heparin therapy combined with coagulation factor replacement was followed by cessation of haemorrhage and complete recovery from acute renal failure.

Ammonia metabolism in chronic obstructive pulmonary disease with special reference to congestive right ventricular failure.

, , 703-709. A study of 36 patients was undertaken to evaluate the role of raised blood and CSF ammonia in the production of central nervous manifestations in chronic obstructive pulmonary disease (COPD) with special reference to congestive right ventricular failure (CRVF). The patient material comprised five categories: 11 controls, seven mentally alert patients with COPD, eight with COPD and CRVF, four with primary cardiac disease and CRVF, and eight with cirrhosis of the liver.