Hypoplastic uterus and clitoris enlargement in Swyer syndrome.

Background: Swyer syndrome is associated with absent testicular differentiation in a 46XY phenotypic female.

Case: A 17-year-old female presented with primary amenorrhea and 46XY karyotype. Breast and pubic hair development were Tanner 2, and clitoral enlargement was noted.

Positive adnexal or uterine serosal involvement in stage IIIC endometrial cancer is an adverse factor for recurrence.

Objectives: Clinical and pathological significance of stage IIIC endometrial cancer is unclear. Our study was designed to determine the risk of recurrence among patients with stage IIIC endometrial cancer according to different pathological findings.

Methods: We retrospectively reviewed all patients with FIGO IIIC endometrial carcinoma (n = 48) treated in our institution between 1996 and 2005.