Publications by authors named "Valerie Giannini"
Article Synopsis
- Multi-drug-resistant tuberculosis (TB) affects around half a million people annually, and current treatments are difficult for patients to follow due to the high number of pills required.
- Researchers have found that nanoparticles made from cross-linked poly-β-cyclodextrins (pβCD) not only serve as effective delivery systems for anti-TB drugs but also exhibit antibacterial properties against Mycobacterium tuberculosis (Mtb).
- These pβCD nanoparticles can reduce Mtb colonization in lung macrophages and promote the death of infected cells, creating an environment less favorable for Mtb persistence, indicating their potential use in TB treatments.
