Synopsis of recent research by authors named "Valerie Calco"
Valerie Calco's research primarily focuses on the role of various proteins and small GTPases in the mechanisms of exocytosis and endocytosis in neuroendocrine cells, with a particular emphasis on calcium-regulated secretion processes.
Her findings highlight the critical involvement of proteins such as Annexin A2 and Oligophrenin-1 in lipid microdomain formation and the coupling of exocytosis with compensatory endocytosis, which is essential for maintaining homeostasis in neurosecretory cells.
Additionally, Calco's work explores the regulatory functions of Rho GTPases like Cdc42 and Rac1, providing insights into their influences on actin dynamics and vesicular trafficking during hormone release in neuroendocrine contexts.
