Publications by authors named "Valerie Bassien-Capsa"
Article Synopsis
- A study found that Afro-Caribbeans have a lower mortality rate from coronary artery disease (CAD) and better lipid profiles compared to Europeans.
- Researchers analyzed 705 Afro-Caribbeans, genotyping them for 13 lipid-related variants while calculating polygenic risk scores for LDL, HDL, and triglycerides.
- The study revealed that higher LDL-PRS was linked to elevated LDL levels and an increased risk of CAD, while HDL-PRS and TG-PRS showed no significant association with CAD.
Cognitive decline and comorbid conditions commonly co-occur, and these conditions can affect cognitive health. We aimed to estimate the prevalence of cognitive impairment (CI) according to weight status and to evaluate the associations between CI, weight status and comorbid conditions in adults of 55 years and older. The Abbreviated Mental Test Score (AMTS) was used.
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- A study in Guadeloupe aimed to determine the prevalence of metabolic syndrome (MetS) among Afro-Caribbean adults without diabetes or cardiovascular issues, using the NCEP ATP III definition.
- Out of 1011 participants (mostly women), the overall MetS prevalence was 17.9%, notably higher in women (21.1%) than men (10.8%), and increased with age, especially in women.
- The findings indicated that adults aged 60 and older had significantly higher odds of hypertension, abdominal obesity, and high fasting blood glucose levels, highlighting the need for preventive measures against MetS, particularly for older adults and women.
Natriuretic peptides, brain natriuretic peptide (BNP), and N-terminal probrain natriuretic peptide (NT-proBNP) are mainly known as diagnostic markers for heart failure with high diagnostic and prognostic values in the general population. In patients who are undergoing hemodialysis (HD), changes in NT-proBNP can be related to noncardiac problems such as fluid overload, inflammation, or malnutrition and can also be influenced by the dialysis characteristics. The current review aimed to summarize findings from studies on the association between NT-proBNP and malnutrition in HD patients.
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- * In a study of 375 Afro-Caribbean nondiabetic subjects, the K656N polymorphism showed significant associations with body mass index (BMI) and waist circumference (WC), but not with leptin levels.
- * Individuals with the K656N variant allele had a higher risk of obesity and abdominal obesity, indicating its potential influence on these conditions in the studied population.
Article Synopsis
- - The study investigates how pregnancy affects heart function in rats, focusing on the role of mineralocorticoids in cardiac adaptations, particularly in late-stage pregnancy.
- - Researchers found that pregnancy leads to changes in cardiac cell metabolism, and inhibiting mineralocorticoid receptors decreases energy substrates like lactate, which affects heart cell contractility without altering calcium current density.
- - The findings suggest that mineralocorticoids are crucial for heart cell adaptations during pregnancy by regulating energy levels and metabolic states, potentially informing future studies on heart health during pregnancy.