Renal transplants from older deceased donors: Is pre-implantation biopsy useful? A monocentric observational clinical study.

Aim: To compare survival of kidney transplants from deceased extended criteria donors (ECD) according to: (1) donor graft histological score; and (2) allocation of high score grafts either to single (SKT) or dual (DKT) transplant.

Methods: Renal biopsy was performed as part of either a newly adopted DKT protocol, or of surveillance protocol in the past. A total 185 ECD graft recipients were categorized according to pre-implantation graft biopsy into 3 groups: SKT with graft score 1 to 4 [SKT, = 102]; SKT with donor graft score 5 to 8 [SKT, = 30]; DKT with donor graft score 5 to 7 (DKT, = 53).

Renal Transplants from Older Deceased Donors: Use of Preimplantation Biopsy and Differential Allocation to Dual or Single Kidney Transplant according to Histological Score Has No Advantages over Allocation to Single Kidney Transplant by Simple Clinical Indication.

Background: Grafts from elderly donors (ECD) are increasingly allocated to single (SKT) or dual (DKT) kidney transplantation according to biopsy score. Indications and benefits of either procedure lack universal agreement.

Methods: A total of 302 ECD-transplants in period from Jan 1, 2000, to Dec 31, 2015, were allocated to SKT (SKT) on clinical grounds alone (before Dec 2010, pre-DKT era, = 170) or according to a clinical-histological protocol (after Dec 2010, DKT era, = 132) to DKT ( = 48), SKT biopsy-based protocol ("high-risk", SKT, = 51), or SKT clinically based protocol ("low-risk", SKT, = 33).