Publications by authors named "Valeria Ovando-Gomez"
Article Synopsis
- The study assessed atherosclerotic risk factors in children aged 2 to 17 in South-Southeast Mexico, focusing on atherogenic indices (AI) and cardiovascular factors.
- The results indicated a high prevalence of atherogenic risk, particularly among preschoolers and adolescents, with specific indices (like LDL-c/ApoB and AIP) showing strong associations with metabolic syndrome and dyslipidemia.
- The findings highlight the need for further research on cardiovascular health in children, emphasizing BMI's role as a significant risk factor and positioning AIP as the most effective index for detecting metabolic issues.
Association of rs662799 and rs5070 genetic polymorphisms with hypertriglyceridemia and atherogenic dyslipidemia in pediatric patients in Southeast Mexico.
Valeria Ovando Gómez Soraya Amalí Zavaleta Muñiz Héctor Ochoa-Díaz-López José Armando Camilo Hernández Contreras Cesar Antonio Irecta Nájera
Clin Investig Arterioscler
April 2023
Background And Aims: Triglycerides are the initiators of the metabolic changes that lead to atherogenic dyslipidemia (AD). The APOA5 and APOA1 genes are involved in the response and metabolism of serum lipids and lipoproteins, where single nucleotide polymorphisms (SNP) rs662799 (promoter region) and rs5070 (intronic region) have been associated with the susceptibility to dyslipidemia. Until now, few studies evaluate the association of these polymorphisms with the presentation of hypertriglyceridemia and AD among Mexican children.
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