Proton therapy monitoring: spatiotemporal emission reconstruction with prompt gamma timing and implementation with PET detectors.

. In this study we introduce spatiotemporal emission reconstruction prompt gamma timing (SER-PGT), a new method to directly reconstruct the prompt photon emission in the space and time domains inside the patient in proton therapy..

Radiotherapy dose enhancement using BNCT in conventional LINACs high-energy treatment: Simulation and experiment.

Aim: To employ the thermal neutron background that affects the patient during a traditional high-energy radiotherapy treatment for BNCT (Boron Neutron Capture Therapy) in order to enhance radiotherapy effectiveness.

Background: Conventional high-energy (15-25 MV) linear accelerators (LINACs) for radiotherapy produce fast secondary neutrons in the gantry with a mean energy of about 1 MeV due to (γ, n) reaction. This neutron flux, isotropically distributed, is considered as an unavoidable undesired dose during the treatment.