Publications by authors named "Valeria Guzzetta"

Introduction: is a prevalent and virulent global pathogen, with colonization being considered a precondition for pneumococcal disease. Understanding colonization is critical for gaining insights into transmission dynamics and developing effective interventions. This study aimed to determine the prevalence of nasopharyngeal colonization and serotype distribution in the Sicilian population.

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Article Synopsis
  • Seasonal influenza poses a public health challenge with socioeconomic impacts, and wastewater-based epidemiology (WBE) is a promising method for monitoring its spread and enhancing public health strategies.
  • In a study conducted in Italy, wastewater samples were analyzed to detect influenza virus RNA, revealing a strong correlation between viral RNA loads and influenza-like illness cases reported in the community.
  • The findings suggest that while WBE is not a substitute for traditional methods, it can significantly enhance the understanding of influenza dynamics and incidence trends.
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Article Synopsis
  • * Researchers analyzed data from migrants collected in Sicily between February 2021 and May 2022, using advanced molecular techniques to identify and categorize various SARS-CoV-2 variants present among the population.
  • * The findings revealed 472 full-length virus sequences, identified 12 clades and 31 lineages, and demonstrated the potential of this molecular surveillance to predict emerging variants, which can help shape vaccination and public health strategies.
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Monitoring the genetic variability of human respiratory syncytial virus (hRSV) is of paramount importance, especially for the potential implication of key antigenic mutations on the emergence of immune escape variants. Thus, to describe the genetic diversity and evolutionary dynamics of hRSV circulating in Sicily (Italy), a total of 153 hRSV whole-genome sequences collected from 770 hRSV-positive subjects between 2017 and 2023, before the introduction of expanded immunization programs into the population, were investigated. The phylogenetic analyses indicated that the genotypes GA.

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