Publications by authors named "Valeria Fiori"
Insomnia has been suggested as a potential modulator of systemic inflammation. However, few studies have examined the longitudinal association between insomnia and inflammation as well as the role of sex differences, despite accumulating evidence of the vulnerability of women to immune consequences of disturbed sleep. In this study, we tested the association between self-reported insomnia symptoms and serum C-reactive protein, a marker of systemic inflammation, at 1-year follow-up, in 54 outpatients with inflammatory bowel disease (52.
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- Adverse Childhood Experiences (ACEs) and Depression
- : Childhood trauma (ACEs) is linked to a higher likelihood of developing depression in adults, and the role of inflammation in this connection is being explored.
- Study Overview and Findings
- : A systematic review involved 22 studies analyzing inflammatory markers (like CRP and IL-6) in relation to ACEs and adult depression. Initial findings indicated that inflammation significantly mediated the ACE-depression link, though this effect diminished when considering body mass index (BMI).
- Complex Interactions Identified
- : Although findings suggest a relationship between ACEs, inflammation, and depression, caution is advised due to the study's cross-sectional nature. The results imply that
Objective: Inflammatory bowel disease (IBD) is often comorbid with mood disorders and depressive symptoms. The aetiology of depressive symptoms in IBD, however, remains largely unknown. Consistent with the inflammatory hypothesis of depression, the aim of this study was to explore the prospective associations between inflammatory biomarkers and depressive symptoms in a cohort of IBD patients with and without a previous clinical diagnosis of mood disorder.
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