[Knowledge level for prescription of nonsteroidal anti-inflammatory by dentists in São José dos Campos, São Paulo State, Brazil].

The abusive use of drugs in clinical routine of dentistry represents a problem of public health. Studies have demonstrated that the effectiveness of anti-hypertensive drugs was decreased by the simultaneous use of Nonsteroidal Anti-Inflammatory Drugs (NAIDs), mainly in elderly patients with primary hypertension. This study was to evaluate the scientific knowledge of the dentists working at the public health service in São José dos Campos, São Paulo, Brazil.

Rational use of antimicrobials in dentistry during pregnancy.

The use of medicines during pregnancy deserves special attention from dentists due to the potential risks to fetal development. The prescription of antimicrobial drugs during this period must be based not only on the etiology of the disease but also on the drug's effect on the embryo, which may be toxic, possibly leading to irreversible lesions. Interest in studies of the teratogenic effects of drugs increased in response to reports of the high incidence of phocomelia in patients treated with thalidomide.

Histomorphometric analysis of homogenous demineralized dentin matrix as osteopromotive material in rabbit mandibles.

Purpose: The aim of this work was to evaluate the effectiveness of homogenous demineralized dentin matrix (HDDM) slices in surgical bone defects created in the mandibles of rabbits and occluded with a polytetrafluoroethylene (PTFE) membrane in the promotion of bone growth.

Materials And Methods: Surgical bone defects were created in 36 adult rabbits and divided into 4 groups: bone defect (control), bone defect with PTFE membrane, bone defect with HDDM, and bone defect with both HDDM and a PTFE membrane (HDDM + PTFE). The rabbits were sacrificed after 30, 60, and 90 days, and the bone defects were examined histologically and by histomorphometric analysis (analysis of variance and the Tukey test).