Leuconostoc mesenteroides strain MS4-derived bacteriocins: A potent antimicrobial arsenal for controlling Xylella fastidiosa infection.

Xylella fastidiosa subsp. pauca (Xfp) currently presents a serious threat to agriculture in Europe and in the Mediterranean, following its discovery in several countries. Addressing this bacterial plant disease with traditional agricultural practices and management strategies has proven inadequate, highlighting the urgent need for effective and environmentally safe antibacterial solutions.

Moving Beyond the Bladder Diary: Does New Technology Now Allow Us to Take Investigation of LUTS Into the Community? ICI-RS 2024.

Context: Lower Urinary Tract Symptoms (LUTS) are defined by their distressing effect on patients' day-to-day life. Given the pressures on secondary care resources, LUTS may be overlooked or inadequately assessed and therefore patients may be burdened for an extended period before treatment.

Methods: In a debate held at the International Consultation on Incontinence Research Society (ICI-RS) meeting in Bristol in June 2024, we considered how new technologies might contribute to an expedited, dignified and effective investigation of LUTS.

Optimization of the Mechanical Recycling of Phenolic Resins for Household Appliances.

In light of the significant impact of climate change, it is imperative to identify effective solutions to reduce the environmental burdens of industrial production and to promote recycling strategies also for thermosetting polymers. In this work, the mechanical recycling of phenolic resins, obtained from industrial production scrap of plastic knobs for household appliances, was optimized. The feasibility of a partial substitution of virgin materials with recycled ones was investigated both at a laboratory and industrial scale.

Enhancing Lettuce () Productivity: Foliar Sprayed Fe-Alg-CaCO MPs as Fertilizers for Aquaponics Cultivation.

Aquaponics is an innovative agricultural method combining aquaculture and hydroponics. However, this balance can lead to the gradual depletion of essential micronutrients, particularly iron. Over time, decreasing iron levels can negatively impact plant health and productivity, making the monitoring and management of iron in aquaponic systems vital.

Reducing drought vulnerability of forest soils using Xanthan gum-based soil conditioners.

Climate change increases the frequency and severity of droughts in many parts of Europe, thereby affecting the availability of water resources. Therefore, preserving the soil water content is essential for maintaining forest diversity and plant vitality. To improve soil hydraulic properties and reduce drought vulnerability, three xanthan-gum-based soil conditioners (SC_R, SC_CG, and SC_ZZC) were developed under the European ONEforest project.

Ni/PiNe Heterogeneous Catalyst from Biomass Waste: Low-Loading, Ligand-Free Suzuki-Miyaura Cross-Coupling.

An efficient Ni-based heterogeneous catalyst from pine needles urban waste valorization was designed and developed with a resource recycling strategy. The Ni/PiNe catalyst was fully characterized and tested in the Suzuki-Miyaura coupling under microwave irradiation. Although Ni is a promising candidate for replacing Pd-based catalytic systems, it generally requires a high catalyst amount and the exploitation of ligands and additives to enhance the reaction rate.

Assessing lung consolidation in goats using different ultrasonographic techniques.

Goats are often affected by respiratory diseases and, despite ultrasonography can assess lung consolidations in several species, it is rarely used in these animals. So, this study evaluated the effectiveness of on-farm lung ultrasonography in detecting lung consolidations on 27 goats. The goats, scheduled for slaughter, underwent complete clinical examinations and lung ultrasonography.

Profiles of Posttraumatic Growth and Posttraumatic Stress Symptoms in Childhood Cancer Survivors.

The experience of childhood cancer (CC) could be a traumatic event that produces long-term emotional responses such as posttraumatic stress symptoms (PTSS) and posttraumatic growth (PTG) in survivors. The relationship between both PTSS and PTG is not clear in CC survivors. Assessing challenges to core beliefs and rumination could give information regarding the different paths that lead to traumatic responses.

phage MATE 2: a novel bacteriophage with potent lytic activity against subsp. .

() is a major phytosanitary threat to global agricultural production. The complexity and difficulty of controlling underscore the pressing need for novel antibacterial agents, i.e.

Nisin-based therapy: a realistic and eco-friendly biocontrol strategy to contrast subsp. infections .

The lack of sustainable strategies for combating () highlights the pressing need for novel practical antibacterial tools. In this study, subsp. strain ATCC 11454 (), known for its production of nisin A, was tested against subsp.

Facile and Bioinspired Approach from Gallic Acid for the Synthesis of Biobased Flame Retardant Coatings of Basalt Fibers.

A sustainable, bioinspired approach to functionalize basalt fibers with an innovative gallic acid (GA)-iron phenyl phosphonate complex (BF-GA-FeP), for the purpose of improving the flame retardancy in composite materials, is developed. BFs were at first pretreated with O, obtaining surface free hydroxyl groups that allowed the subsequent covalent immobilization of biosourced GA units on the fiber through ester linkages. Phenolic -OH groups of the GA units were then exploited for the complexation of iron phenyl phosphonate, resulting in the target-complex-coated BF fiber (BF-GA-FeP).

The Brazilian version of the Inventory of Depression and Anxiety Symptoms-Expanded Version: Internal structure, invariance by sex and race, and associations with pathological personality traits.

The Inventory of Depression and Anxiety Symptoms-Expanded version (IDAS-II) is one of the few tools designed to assess internalizing symptoms based on dimensional models. We conducted two studies, the first testing internal validity aspects of the IDAS-II and the second testing the external validity of the scales. In the first study we adapted the IDAS-II to Brazilian Portuguese and tested its internal structure, including a higher order factorial solution coherent with the internalizing spectrum, the stability of the factor structure, and its measurement invariance for sex and racial groups.

Pembrolizumab-based first-line treatment for PD-L1-positive, recurrent or metastatic head and neck squamous cell carcinoma: a retrospective analysis.

Background: The KEYNOTE-048 trial showed that pembrolizumab-based first-line treatment for R/M HNSCC led to improved OS in the PD-L1 CPS ≥ 1 population when compared to the EXTREME regimen. However, the R/M HNSCC real-world population is generally frailer, often presenting with multiple comorbidities, worse performance status and older age than the population included in phase III clinical trials.

Methods: This is a retrospective, single-centre analysis of patients with R/M HNSCC treated with pembrolizumab-based first-line treatment.

Biological Effects of Small Sized Graphene Oxide Nanosheets on Human Leukocytes.

Since the discovery of graphene, there has been a wide range of the literature dealing with its versatile structure and easy binding of biomolecules as well as its large loading capacity. In the emerging field of immunotherapy, graphene and its derivatives have potential uses as drug delivery platforms directly into tumour sites or as adjuvants in cancer vaccines, as they are internalized by monocytes which in turn may activate adaptive anti-tumoral immune responses. In this study, we expose cells of the innate immune system and a human acute monocytic leukemia cell line (THP-1) to low doses of small-sized GO nanosheets functionalized with bovine serum albumin (BSA) and fluorescein isothiocyanate (FITC), to study their acute response after internalization.

Is the time right for a new initiative in mathematical modeling of the lower urinary tract? ICI-RS 2023.

Introduction: A session at the 2023 International Consultation on Incontinence - Research Society (ICI-RS) held in Bristol, UK, focused on the question: Is the time right for a new initiative in mathematical modeling of the lower urinary tract (LUT)? The LUT is a complex system, comprising various synergetic components (i.e., bladder, urethra, neural control), each with its own dynamic functioning and high interindividual variability.

Effect of Different Cellulose Fillers on the Properties of Xanthan-Based Composites for Soil Conditioning Applications.

The aim of this study was to investigate the effect of different types of natural cellulose-based fillers on the properties of Xanthan gum (XG) in order to develop novel bio-based soil conditioners (SCs) that could be used in forestry and agricultural applications. Rheological measurements highlighted that SCs with cellulose fillers characterized by a high aspect ratio and low oxide ash content exhibited an average increase of 21% in yield stress compared to neat Xanthan gum. The presence of cellulose fillers in the composites resulted in a slower water release than that of neat XG, limiting the volumetric shrinkage during the drying process.

Zoonotic Microparasites in Invasive Black Rats () from Small Islands in Central Italy.

Invasive species have a detrimental impact on native populations, particularly in island ecosystems, and they pose a potential zoonotic and wildlife threat. Black rats () are invasive species that disrupt native flora and fauna on islands and serve as potential competent reservoirs for various pathogens and parasites. Microparasites screening was conducted in rat populations from small islands in central Italy (the Pontine Islands and Pianosa) with the aim of assessing the role of rats in maintaining infections, particularly in cases where key reservoir hosts were scarce or absent.

Efficient synthesis and investigation of waste-derived adsorbent for water purification. Exploring the impact of surface functionalization on methylene blue dye removal.

In pursuit of sustainable water management, the preparation of adsorbent materials via waste upcycling for water purification practices plays a decisive role. The sulphonated biochar, PiNe-SOH, employed to target the methylene blue dye adsorption, was successfully synthesized via a mild, step-economical chemical carbonization-functionalization reaction. The presence of SOH groups on the PiNe-SOH surface played a critical role in significantly enhancing the adsorption capacity.

Zinc Oxide Nanoparticles Biosynthesized by Leaf Extract: Characterization, Insecticidal and Antibacterial Properties.

Zinc oxide nanoparticles (ZnO-NPs) have gained significant attention in nanotechnology due to their unique properties and potential applications in various fields, including insecticidal and antibacterial activities. The ZnO-NPs were biosynthesized by leaf extract and characterized by various techniques such as UV-visible (UV-vis) spectrophotometer, X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), and zeta potential analysis. The results of SEM revealed that NPs were irregular and spherical-shaped, with a diameter between 5 and 27 nm.

A General Enantioselective C-H Arylation Using an Immobilized Recoverable Palladium Catalyst.

We herein report a general and efficient enantioselective C-H arylation of aryl bromides based on the use of BozPhos as the bisphosphine ligand and SP-NHC-Pd as recoverable heterogeneous catalyst. By exploiting the "release and catch" mechanism of action of the catalytic system, we used BozPhos as a broadly applicable chiral ligand, furnishing high enantioselectivities across all types of examined substrates containing methyl, cyclopropyl and aryl C-H bonds. For each reaction, the reaction scope was investigated, giving rise to 30 enantioenriched products, obtained with high yields and enantioselectivities, and minimal palladium leaching.

Semi-Quantitative Risk Assessment of African Swine Fever Virus Introduction in Outdoor Pig Farms.

In a previous study, a semi-quantitative risk assessment was developed to rank pig holdings in terms of likelihood of introducing African swine fever virus (ASFV) by assessing their compliance with biosecurity and exposure to geographical risk factors. The method was initially developed for confined pig holdings, but given that ASF is endemic in wild boar of several countries, we modified the approach to make it suitable for free-range farms as well. In the current study, a total of 41 outdoor pig farms were assessed in an area where exposure to wild boar was generally high (density from 2.

Elbow trauma in children: development and evaluation of radiological artificial intelligence models.

Rationale And Objectives: To develop a model using artificial intelligence (A.I.) able to detect post-traumatic injuries on pediatric elbow X-rays then to evaluate its performances in silico and its impact on radiologists' interpretation in clinical practice.