Publications by authors named "Valentine Siba"
Background: The Highlands of Papua New Guinea are non-endemic for malaria compared to the rest of the country. This study aimed to explore the local transmission of malaria in the Highlands through a cross-sectional school survey coupled with reactive case detection.
Methods: Between July and November 2019, 5575 schoolchildren and 1048 household members were screened for malaria using Rapid Diagnostic Tests, subsequently validated by light microscopy.
Article Synopsis
- Typhoid fever, caused by Salmonella enterica serovar Typhi, remains a major health issue in low-income regions, particularly in the Asia-Pacific, and this study analyzes the S. Typhi populations in Papua New Guinea (PNG) over 30 years using whole genome sequencing.
- The research found that PNG's S. Typhi is primarily made up of a single genotype (2.1.7) that originated in Indonesia, showing low evidence of cross-border transmission, and remains largely susceptible to traditional treatment drugs.
- To effectively combat typhoid fever, PNG needs to maintain effective antimicrobial treatments while improving sanitation infrastructure and monitoring for any signs of antimicrobial resistance (AMR) emergence.
Introduction: Diarrhoea remains a major cause of illness in Papua New Guinea (PNG); however, little is known about its aetiology. As a result of the cholera outbreak that spread throughout PNG in 2009-2011, we conducted diarrhoeal surveillance in Eastern Highlands Province.
Methodology: Following informed consent and a brief questionnaire, participants provided a stool sample or duplicate rectal swabs.
Typhoid fever remains a major global health problem. A major impediment to improving outcomes is the lack of appropriate diagnostic tools, which have not significantly improved in low-income settings for 100 years. We evaluated two commercially available rapid diagnostic tests (Tubex and TyphiDot), a prototype (TyphiRapid TR-02), and the commonly used single-serum Widal test in a previously reported high-burden area of Papua New Guinea.
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