Publications by authors named "Valentina Zadro"

Article Synopsis
  • * A survey involved 47 out of 128 Italian centers, revealing a CIF prevalence of about 1%, with higher rates in academic settings and only a small percentage of centers routinely conducting necessary assessments.
  • * Although 12 centers used the medication teduglutide (TED) with a reported success rate of over 50%, overall management of SBS and CIF was found to be inadequate in the participating centers.
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Background: Current guidelines strongly recommend the use of validated classifications to support optical diagnosis of lesions with advanced endoscopic imaging in the lower gastrointestinal tract. However, the optimal strategy in inflammatory bowel disease (IBD) is still a matter of debate.

Objectives: To analyze the accuracy of endoscopic classifications or single predictors for lesion characterization during endoscopic surveillance of IBD with advanced endoscopic imaging.

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Article Synopsis
  • A study compared the effectiveness of four biologic drugs—adalimumab, infliximab biosimilar, golimumab, and vedolizumab—used to treat ulcerative colitis (UC) in Italy, focusing on achieving continuous clinical remission (CCR).
  • Researchers analyzed data from 416 UC patients treated from 2014 to 2019, measuring success based on a strict CCR definition over one year.
  • Results showed similar CCR rates among the four drugs, with vedolizumab proving more effective for patients who had previously failed anti-TNFα treatments, while safety profiles were comparable across all drugs.
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