Publications by authors named "Valentina Rojas"
Article Synopsis
- Autism spectrum disorder (ASD) is linked to mitochondrial dysfunction, which involves increased mitochondrial DNA (mtDNA) copy number and energy production issues; this study focused on key genes related to mtDNA replication to understand their role in ASD.
- Children with ASD showed higher mtDNA copy numbers and some mtDNA deletions in oral samples, but no significant changes were found in the expression of mitochondrial replisome genes compared to typically developing controls.
- Increased oxidative stress and inflammation were noted in ASD subjects, and while overexpressing the TFAM gene in cell cultures led to some mitochondrial benefits, this didn't directly tie to changes in gene expression or mtDNA integrity, indicating a complex relationship between mitochondrial dysfunction and ASD.
The greater wax moth, , is a global pest for beehives, doing damage in the larval stage. Although a significant number of studies have reported on larvae and adults, to date no effective pest control has been implemented. In this study, we tested larval resistance to alkaloids from , and the objective was to identify enzymes that participate in alkaloid detoxification through enzymatic assays, bioinformatics analysis and qRT-PCR.
View Article and Find Full Text PDFIntroduction: Cardiovascular risk (CVR) is defined as the possibility of a subject suffering from car diovascular disease within a certain period. Although the pathology appears in adult life, the physiopathological changes start to develop at an early age.
Objective: To establish the relationship bet ween cardiorespiratory capacity (CRC)and CVR in children with metabolic syndrome.
In reptiles, arginine vasotocin (AVT) impacts the performance of and response to visual social signals, but whether AVT also operates within the chemosensory system as arginine vasopressin (AVP) does in mammals is unknown, despite social odors being potent modifiers of competitive and appetitive behavior in reptiles. Here, we ask whether elevated levels of exogenous AVT impact rates of chemical display behavior (e.g.
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- The study aimed to evaluate how Community-Based Rehabilitation (CBR) is implemented in Chile, focusing on 66 rehabilitation centers in the Metropolitan Region as of December 2016.
- Researchers used a self-administered questionnaire aligned with the World Health Organization's CBR matrix, gathering responses from center coordinators through online surveys.
- Results showed a varied implementation of CBR components, with Health being the most developed, while Social, Livelihood, and Empowerment were moderate, and Education was the least addressed; improvements are needed in these areas for better social inclusion of individuals with disabilities.
Analysis of the grapevine moth Lobesia botrana antennal transcriptome and expression of odorant-binding and chemosensory proteins.
Comp Biochem Physiol Part D Genomics Proteomics
September 2018
The grapevine moth, Lobesia botrana, is considered a harmful pest for vineyards in Chile as well as in North America and Europe. Currently, monitoring and control methods of L. botrana are based on its main sex pheromone component, being effective for low population densities.
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