Publications by authors named "Valentin Zumstein"

Purpose: To assess efficacy and safety of prostatic artery embolization (PAE) in patients with advanced prostate cancer (PCa).

Materials And Methods: In this prospective single-center, single-arm, pilot study, 9 men with advanced PCa underwent PAE. PAE was performed with the use of 250-400 µm Embozene microspheres (Boston Scientific, Natick, Massachusetts, USA).

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Context: Radiotherapy of the pelvis is a widely used method for the treatment of malignancies, and local complications including pain following pelvic radiation therapy are acknowledged complications.

Objective: The primary objective is to assess the clinical effectiveness and safety of pharmacological therapies on postradiation pelvic pain.

Evidence Acquisition: A systematic review of the use of different pharmacological treatments in the management of post-radiation pelvic pain was conducted (PROSPERO-ID: CRD42021249026).

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Context: Prostatic artery embolization (PAE) is increasingly performed worldwide for the treatment of lower urinary tract symptoms (LUTS) secondary to benign prostatic obstruction (BPO). In contrast, the role of PAE in patients with prostate cancer (PCa) is unclear.

Objective: This systematic review summarizes the current available literature on PAE in patients with PCa regarding oncological and functional outcome.

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Article Synopsis
  • - The study aimed to evaluate how well men undergoing surgery for lower urinary tract symptoms (LUTS) due to benign prostatic obstruction (BPO) achieved their personal health goals, comparing this to traditional outcome measures used in such treatment.
  • - Researchers analyzed data from 68 patients who set individual goals and completed traditional questionnaires pre-surgery and at a follow-up 6-12 weeks later, finding strong correlations between self-assessed goal achievement and established questionnaires like the IPSS.
  • - The results suggest that self-assessed goals (SAGA) provide a more patient-centered perspective on treatment outcomes, highlighting that functional measures may not capture what patients uniquely aim to achieve.
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Female urethral stricture is a rare manifestation of bladder outlet obstruction in women. According to the current guidelines of the European Association of Urology, urethral dilatation should be offered as first line treatment. Intermittent self-dilatation (ISD) in case of recurrence is recommended.

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Context: Despite the high prevalence of a myofascial pain component in chronic pelvic pain (CPP) syndromes, awareness and management of this component are lacking among health care providers.

Objective: To summarize the current state of the art for the management of myofascial pain in chronic primary pelvic pain syndromes (CPPPS) according to scientific research and input from experts from the European Association of Urology (EAU) guidelines panel on CPP.

Evidence Acquisition: A narrative review was undertaken using three sources: (1) information in the EAU guidelines on CPP; (2) information retrieved from the literature on research published in the past 3 yr on myofascial pelvic pain; and (3) expert opinion from panel members.

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Introduction: Male reproductive health is rapidly declining during the past decades and it is well known that scrotal temperature is linked to male infertility.

Material And Methods: We performed a prospective data evaluation within a counterfactual analysis study design. Scrotal cooling was performed using Snowballs™ underwear, scrotal temperature was monitored using a wireless temperature sensor (SensorPush, Brooklyn, NY, 11215).

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Management of chronic pelvic pain (CPP) remains a huge challenge for care providers and a major burden for healthcare systems. Treating chronic pain that has no obvious cause warrants an understanding of the difficulties in managing these conditions. Chronic pain has recently been accepted as a disease in its own right by the World Health Organization, with chronic pain without obvious cause being classified as chronic primary pain.

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Purpose Of Review: Treatment of penile and distal urethral strictures including the fossa navicularis and the meatus remains challenging due to their adverse etiology and lack of ventral tissue support. In this contemporary review, we summarize the available evidence and recent advancements in reconstructive techniques.

Recent Findings: Over the last years, several refinements of already established techniques have been added to the reconstructive armamentarium in the management of penile urethral strictures.

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Introduction: A novel method for the surgical treatment of benign prostatic hyperplasia (BPH) called Aquablation has become commercially available. Previous studies have been able to show similar functional results when compared with transurethral resection of the prostate and a high efficacy has been demonstrated when this approach is applied to patients with a prostate size of 80-150 cm.Holmium laser enucleation of the prostate (HoLEP) is a well-established procedure in the surgical treatment of BPH in prostate glands larger than 30 mL and a first-line therapy in glands over 80 mL.

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Purpose: To evaluate the interplay of stricture recurrence, sexual function, and treatment satisfaction after substitution urethroplasty.

Methods: Observational study of men undergoing 1-stage buccal mucosal graft urethroplasty for anterior urethral stricture between 2009 and 2016. Patients were dichotomized by self-reported treatment satisfaction.

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Context: Patients with chronic pelvic pain syndrome (CPPS) may have pain refractory to conventional management strategies. Botulinum toxin A (BTX-A) is a potential therapeutic option.

Objective: To evaluate the benefits and harms of BTX-A injections in the treatment of CPPS.

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Purpose: To assess migration of urinary stones with ureteral stents in place.

Materials And Methods: We performed a retrospective analysis of stone characteristics and locations in patients treated with secondary retrograde intrarenal surgery for symptomatic urinary stones at our institution. We analyzed 393 patients with a median age of 53 years and a median stone size of 7 mm.

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Objectives: To compare a customized 'suture stent' with a standard ureteric stent regarding stent-related symptoms, safety and efficacy.

Materials And Methods: Patients with urolithiasis located proximal to the iliac vessel crossing, requiring stenting in preparation for secondary ureterorenoscopy (URS) were randomized to standard ureteric stenting or a suture stent. Secondary ureterorenoscopy was performed 2-6 weeks later.

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Article Synopsis
  • The study evaluated the quality of YouTube videos on the surgical treatment of urinary stones using validated tools to assess misinformation and conflicts of interest.
  • Out of 100 videos analyzed, most had low quality ratings, with only 26 free from misinformation and only 9 disclosing conflicts of interest.
  • Videos from healthcare professionals and medical organizations, particularly the European Association of Urology (EAU), were found to be of significantly higher quality, emphasizing the need for high-quality, evidence-based patient education.
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Although evidence supporting the efficacy and safety of prostatic artery embolisation (PAE) is increasing, potential associated risks of ionising radiation in this context remain largely unknown. We systematically reviewed reports on radiation exposure (RE) during PAE in the literature and estimated the risk RE poses using a Monte Carlo dose calculation algorithm. Of 842 studies screened, 22 were included.

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Objectives: To evaluate objective treatment success and subjective patient-reported outcomes in patients with radiation-induced urethral strictures undergoing single-stage urethroplasty.

Patients And Methods: Monocentric study of patients who underwent single-stage ventral onlay buccal mucosal graft urethroplasty for a radiation-induced stricture between January 2009 and December 2016. Patients were characterized by descriptive analyses.

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Objectives: To assess the quality of videos on the surgical treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia (LUTS/BPH) available on YouTube, given that such video-sharing platforms are frequently used as sources of patient information and the therapeutic landscape of LUTS/BPH has evolved substantially during recent years.

Materials And Methods: A systematic search for videos on YouTube addressing treatment options for LUTS/BPH was performed in May 2019. Measures assessed included basic data (e.

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Objectives: To describe the operative technique and report outcomes from the largest series of patients who underwent single-stage dorsal inlay buccal mucosal graft urethroplasty (BMGU) for isolated meatal stenoses and fossa navicularis strictures.

Patients And Methods: First, we evaluated patients who underwent single-stage BMGU for distal urethral strictures (meatus and fossa navicularis) between 2009 and 2016 at our department. Clinical and surgical characteristics were prospectively collected in an institutional database.

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This study compares the findings of different detection methods for microorganisms in patients with ureteral stents undergoing secondary ureterorenoscopy including the use of a novel validated examination pipeline for biofilms on ureteral stents. Of the included 94 patients, 21.3% showed bacteriuria in preoperative urine cultures.

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Purpose: We intended to assess the readability of the German versions of commonly used urological questionnaires and identify questions that are potentially demanding for patients.

Materials And Methods: The Guidelines of the European Association of Urology were analyzed for recommended questionnaires. Readability of the German versions of these questionnaires including their respective single-items was analyzed using established readability assessment tools.

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