Cryopreservation: an optimizing factor for therapeutic potential of fetoplacental complex products.

The therapeutic potential of cryopreserved fetoplacental complex cells (FPCP) has been explored for the treatment of autoimmune diseases, including autoimmune hemolytical anemia (AIHA). In this study, a murine AIHA model was utilized to investigate the application of cryopreserved fetal liver cells (cFLC), from varying gestation intervals (14 and 19 postcoital days) to correct the functional state of the lymphohemopoietic complex (LHPC). The results demonstrate that cryopreservation had little negative effect on FLC-14 corrective ability from that of nonfrozen FLC-14.