Publications by authors named "Valentin A Slesarenko"
Article Synopsis
- * This study explored two vaccine candidates, cNHBA and MetQ, aiming to enhance their immune response by creating fusions with MetQ protein fragments, using aluminium hydroxide as an adjuvant for better vaccine production and efficacy.
- * Results showed that these fusions triggered strong immune responses in mice, leading to significant bacterial killing and a reduction in bacterial adherence, identifying MetQ-cNHBA and cNHBA-Met2 as the most promising candidates for future vaccine development against gonorr
Neisseria gonorrhoeae is an increasing public health threat due to its rapidly rising incidence and antibiotic resistance. There are an estimated 106 million cases per year worldwide, there is no vaccine available to prevent infection, and N. gonorrhoeae strains that are resistant to all antibiotics routinely used to treat the infection have emerged.
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