Breast-milk iodine concentration declines over the first 6 mo postpartum in iodine-deficient women.

Background: Little is known about the iodine status of lactating mothers and their infants during the first 6 mo postpartum or, if deficient, the amount of supplemental iodine required to improve status.

Objective: The objective was to determine maternal and infant iodine status and the breast-milk iodine concentration (BMIC) over the first 6 mo of breastfeeding.

Design: A randomized, double-blind, placebo-controlled supplementation trial was conducted in lactating women who received placebo (n = 56), 75 μg I/d (n = 27), or 150 μg I/d (n = 26) after their infants' birth until 24 wk postpartum.

Serum thyrotropin and free thyroxine reference ranges as defined in a disease-free sample of French middle-aged adults.

Background: The goal of this study was to provide reference ranges for thyrotropin (TSH) and free thyroxine (fT(4)) based on data collected from a disease-free sample of French middle-aged adults.

Methods: A total of 3218 subjects participating in the Supplémentation en Vitamines et Minéraux Antioxydants (SU.VI.

Lifestyle factors related to iodine intakes in French adults.

Objective: To assess dietary iodine intakes among adults and to investigate the relationships of dietary, lifestyle, demographic and geographical characteristics with dietary iodine status. Adequacy of iodine intakes was also assessed.

Design: Cross-sectional study.

[Difference in urine concentration according to gender and ethnicity: possible involvement in the different susceptibility to various renal and cardiovascular diseases].

Men and African-Americans are known to be at greater risk of urolithiasis and cardiovascular and renal diseases than women and Caucasians. Previous studies suggest that the antidiuretic effects of vasopressin and/or a greater urine concentration are associated with the rate of progression of these diseases. The present review addresses possible sex and ethnic-related differences in urine volume and osmolality which could participate in this male and black higher predominance.

Effects of light to moderate alcohol consumption on thyroid volume and thyroid function.

Objective: To examine a possible relationship between alcohol consumption and thyroid volume and function.

Subjects: A total of 1493 subjects (599 males aged 45-60 years and 894 females aged 35-60 years) with no known thyroid disorders who were participating in the SUpplémentation en VItamines et Minéraux AntioXydants (SU.VI.

Sex difference in urine concentration across differing ages, sodium intake, and level of kidney disease.

Men are known to be at greater risk of urolithiasis and cardiovascular and renal diseases than women. Previous studies suggest that greater urine concentration is associated with acceleration of progression of chronic kidney disease (CKD), increased urinary albumin excretion, and delayed renal sodium excretion. The present review addresses possible sex-related differences in urine volume and osmolality (U(osm)) that could participate in this male risk predominance.

Are breast-fed infants and toddlers in New Zealand at risk of iodine deficiency?

Objective: This study assessed the iodine status of New Zealand infants and toddlers and explored factors that might influence their iodine status.

Methods: A community-based, cross-sectional survey of 6- to 24-mo-old children was conducted in three cities in the South Island of New Zealand. Iodine status was determined by a casual urine sample.

[Thyroid hormone levels and thyroid dysfunction of French adults participating in the SU.VI.MAX study].

Abnormal thyroid function has important public health consequences. However, the various degrees of thyroid dysfunction remain unsettled. The SU.

Association of selenium with thyroid volume and echostructure in 35- to 60-year-old French adults.

Objective: To investigate the relationship between selenium status, thyroid Volume and gland echostructure.

Design: Cross-sectional.

Methods: In 792 men (45-60 Years) and 1108 women (35-60 Years) from the SU.

[Ultrasonic assessment of thyroid nodules, and iodine status of French adults participating in the SU.VI.MAX study].

Thyroid nodules were assessed by ultrasound in 3 621 presumably healthy free-living French subjects participating in the SU.VI.MAX cohort (2 160 females aged 35-60 years and 1 461 males aged 45-60 years).

Determinants of thyroid volume in healthy French adults participating in the SU.VI.MAX cohort.

Objective: To study the relative importance of determinants of thyroid volume.

Design: Cross-sectional study on a sample of subjects issued from the SU.VI.

Determining factors in the iron status of adult women in the SU.VI.MAX study. SUpplementation en VItamines et Minéraux AntioXydants.

The iron status of a national sample of adults living in France and participating in the SU.VI.MAX cohort, was assessed using serum ferritin and hemoglobin concentrations.

Effects of supplementation with a combination of antioxidant vitamins and trace elements, at nutritional doses, on biochemical indicators and markers of the antioxidant system in adult subjects.

Objective: To test the impact of supplementation with nutritional doses of antioxidant nutrients on biochemical indicators of vitamin and trace element levels.

Design: A randomized double-blind trial was performed comparing two groups receiving daily either a combination of vitamins (beta-carotene, 6 mg; vitamin C, 120 mg; and vitamin E, 30 mg) and trace elements (zinc, 20 mg; and selenium, 100 micrograms); or a placebo.

Subjects: 401 subjects (166 males aged 45 to 60 years and 235 females aged to 35 to 60 years).

Dietary magnesium intake in a French adult population.

Magnesium intake was assessed using six 24-h dietary records during a 1-year period in 5,448 subjects (3,111 women 35-60 yrs old and 2,337 men 45-60 yrs old) in the SU.VI.MAX cohort, selected at a national level in France.

Relationship between urinary iodine concentration and hearing capacity in children.

Urinary iodine excretion was assessed in 1222 healthy children aged 10 months (n = 456), 2 years (n = 368) and 4 years (n = 398) living in the Paris area and originating from continental France (55.2%), North Africa (15.7%), the West Indies (9.

Iodine intakes assessed by urinary iodine concentrations in healthy children aged ten months, two years, and four years.

Urinary iodine excretion was assessed in 642 healthy children aged 10 mo (n = 243), 2 yr (n = 183), and 4 yr (n = 216) living in the Paris area and originating from continental France (60.3%), North Africa (13.8%), the West Indies (9.

[Oral and intravenous bepridil in the treatment of recurrent sustained ventricular tachycardias. Electropharmacological study].

The antiarrhythmic properties of bepridil on ventricular tachycardia (VT) termination and prevention were studied in 16 patients using programmed electrical stimulation techniques. All patients were admitted for documented sustained VT resistant to 3.5 +/- 2.