Recurring desmoid tumor of the neck: A case report.

The infiltrative growth pattern of desmoid tumors and their proximity to important anatomical structures make them difficult to manage. Mutilating surgery should be avoided, while surveillance or radiotherapy remain valid options.

Challenging diagnosis of cervical vagal nerve schwannoma.

Schwannoma arising from vagal nerve is a rare tumour. It is a slow-growing, benign mass, but rarely it might undergo malignant transformation. We report a case of a 55-year-old woman with asymptomatic Xth cranial nerve schwannoma in the left side of the neck.

Papillary Thyroid Carcinoma Tissue miR-146b, -21, -221, -222, -181b Expression in Relation with Clinicopathological Features.

We analyzed miR-146b, miR-21, miR-221, miR-21, and miR-181b in formalin fixed paraffin-embedded papillary thyroid carcinoma (PTC) tissue samples of 312 individuals and evaluated their expression relationship with clinicopathological parameters. A higher expression of miR-21 was related to unifocal lesions ( < 0.011) and autoimmune thyroiditis (0.

Different stability of miRNAs and endogenous control genes in archival specimens of papillary thyroid carcinoma.

Background: The most popular miRNA quantitation technique is RQ-PCR with relative gene expression method that requires an endogenous control (EC) gene for data normalization. However, there are insufficient data and selection criteria on the most suitable ECs for miRNA expression studies in many cancer types including papillary thyroid carcinoma (PTC). Therefore, in this study we evaluated the impact of chosen EC and archival formalin-fixed, paraffin-embedded (FFPE) PTC tissue age on estimated target miRNA expression.

Plasma-Derived miRNA-222 as a Candidate Marker for Papillary Thyroid Cancer.

We analyzed five miRNA molecules (miR-221; miR-222; miR-146b; miR-21; miR-181b) in the plasma of patients with papillary thyroid cancer (PTC), nodular goiter (NG) and healthy controls (HC) and evaluated their diagnostic value for differentiation of PTC from NG and HC. Preoperative PTC plasma miRNA expression ( = 49) was compared with plasma miRNA in the HC group ( = 57) and patients with NG ( = 23). It was demonstrated that miR-221; miR-222; miR-146b; miR-21 and miR-181b were overexpressed in preoperative PTC plasma samples compared to HC ( < 0.

A case report of malignant primary pericardial mesothelioma with atypical imaging appearance: multimodality imaging with histopathological correlation.

Background: Primary pericardial mesothelioma is a rare primary cardiac malignancy, with three main histopathological types, sarcomatoid histotype being the rarest. The imaging features were atypical due to concomitant extensive calcification, which resulted in aggravated differential diagnosis.

Case Summary: A 45-year-old man presented to our hospital with non-specific clinical symptoms.

Association of MicroRNA Expression and BRAF Mutation with Recurrence of Thyroid Cancer.

Many miRNAs and cancer-related mutations have been proposed as promising molecular markers of papillary thyroid carcinoma (PTC). However, there are limited data on the correlation between miRNA expression, BRAF mutation, and PTC recurrence. Therefore, to evaluate the potential of BRAF mutation and five selected miRNAs (-146b, -222, -21, -221, -181b) in predicting PTC recurrence, these molecular markers were analyzed in 400 formalin-fixed, paraffin-embedded PTC tissue specimens.

Spontaneous regression of laryngeal carcinoma in 10 year old boy: A case report and review of literature.

Laryngeal carcinoma is a rare pathology in children, with only 92 cases reported. Spontaneous regression of laryngeal carcinoma is even more unique clinical event, so far only observed in adults. In this report we present an extraordinary case of a 10 year old patient with laryngeal squamous cell carcinoma that underwent spontaneous regression.

Correlation between throat-related symptoms and histological examination in adults with chronic tonsillitis.

Objective: The aim of the study was to evaluate correlations between throat-related symptoms and histological findings in adults with chronic tonsillitis.

Materials And Methods: A prospective cohort study was carried out. Throat-related symptoms (complaints, tonsillitis rate, and pharyngeal findings) of 81 adults with histologically proven chronic tonsillitis followed by tonsillectomy were analyzed.

The most important throat-related symptoms suggestive of chronic tonsillitis as the main indication for adult tonsillectomy.

Background And Objective: The literature lacks data about the evaluation of throat-related symptoms proving chronic tonsillitis as the most common indication for adult tonsillectomy. Therefore, the aim of this study was to assess the most important throat-related symptoms suggestive of chronic tonsillitis in adults.

Material And Methods: A prospective cohort study was carried out.

The role of mutation status of the epidermal growth factor receptor gene in advanced non-small cell lung cancer.

Objective: The aim of this study was to examine the prevalence of epidermal growth factor receptor (EGFR) gene mutations among patients with advanced nonsquamous non-small cell lung cancer (NSCLC) treated in our institution and to evaluate the associations between EGFR mutations and clinicopathological characteristics.

Materials And Methods: A total of 103 patients with NSCLC were examined from April 2010 to September 2011. The patients were screened for EGFR mutations in exons 19 and 21 using sequence analysis.

Primary epithelioid sarcoma of the neck: a rare case report.

This report presents a case of a neck epithelioid sarcoma in a 20-year-old man with poor prognosis. The patient underwent surgery followed by external beam radiotherapy and brachytherapy performed as a boost. The treatment was well-tolerated, and there was no local recurrence or distant metastasis.

[Distribution of the epicardiac neural ganglia in human fetuses of different age].

Objective: The epicardiac neural ganglia of the adult human heart are distributed in the seven neural ganglionated subplexuses. The aim of the present investigation was to determine the distribution of the epicardiac ganglia in human fetuses of different age, because intrinsic cardiac nervous system of the human fetus has not been enough investigated so far.

Material And Methods: In the present study seventeen human fetus hearts were investigated, in which epicardiac neural ganglionated plexus was visualized by histochemical method for acetylcholinesterase.

[Correlation of power Doppler sonography with vascularity of the synovial tissue].

The purpose of this study was to investigate the intra-articular vascularization of the synovium with power Doppler sonography and correlate these findings with histopathologic al findings of synovial vascularity. Before arthroplasty or arthroscopy with synovectomy the knee joints of 20 patients with osteoarthritis or rheumatoid arthritis were examined with power Doppler sonography. Vascularity of the synovial membrane was classified semi quantitatively.