Cardiomyopathy and Sudden Cardiac Death: Bridging Clinical Practice with Cutting-Edge Research.

Sudden cardiac death (SCD) prevention in cardiomyopathies such as hypertrophic (HCM), dilated (DCM), non-dilated left ventricular (NDLCM), and arrhythmogenic right ventricular cardiomyopathy (ARVC) remains a crucial but complex clinical challenge, especially among younger populations. Accurate risk stratification is hampered by the variability in phenotypic expression and genetic heterogeneity inherent in these conditions. This article explores the multifaceted strategies for preventing SCD across a spectrum of cardiomyopathies and emphasizes the integration of clinical evaluations, genetic insights, and advanced imaging techniques such as cardiac magnetic resonance (CMR) in assessing SCD risks.

A dew point signaller for conservation of works of art.

All works of art, from paintings, frescoes, sculptures, to monuments and buildings, are affected by diurnal and seasonal variations of the local microclimate, which induce interactions with the environmental atmosphere. Heat and vapour exchanges cause fluxes of heat and mass between the surface and the atmosphere, and may favour the agressivity of environmental pollutants. Condensation-evaporation cycles are recognized as being very important processes which adversely affect the life-time of the work of art.

Coulometric titration by a controlled-potential pulsed-charge potentiometric technique-II Acid-base, precipitation and homogeneous redox systems.

An unconventional coulometric method, based on electrolysis at controlled potential by means of discrete charge-pulses, with end-point detection obtained by mathematical linearization of potentiometric data, has been applied to various systems. The results appear very satisfactory: very weak acids can be determined with high accuracy; in the case of precipitation reactions the selectivity is high enough to allow titration of the components of halide mixtures; for homogeneous redox systems some problems caused by irreversibility at the indicator electrode are overcome.

Coulometric titration by means of a controlled-potential-pulsed-current potentiometric technique-I Metal ions by electro-deposition.

A new method for electrochemical titrations is proposed, based on the redox transformation of the test species by means of a controlled-potential pulsed current, followed by measurement of the potential in the intervals between the current pulses: the end-point is found by means of Sörensen's linearization technique. Investigations on various metal ions (Ag(+), Cu(2+), Cd(2+), Pb(2+)) have shown that the accuracy and sensitivity, which depend on the nature of the species titrated, are comparable with those of other titration techniques. The method permits analytical separations and determinations of metal ions in mixtures.