Giant cutaneous plasmacytoma of the sacrococcygeal region.

Background: Cutaneous plasmacytoma is a very rare manifestation of extramedullary plasmacytoma, with only 32 cases having been reported so far in the last 60 years. Extramedullary plasmacytoma is a plasma cell tumor that involves soft tissues, without any signs of systemic spread of multiple myeloma or bone marrow involvement. The cutaneous lesions usually range in diameter from 1 to 5 cm and can be treated with radiotherapy or surgical excision.

Colchicine treatment of liver fibrosis.

Background/aims: Because of its antifibrotic and anti-inflammatory effects, colchicine has been proposed as a treatment for liver disease. The results from clinical trials have however been inconsistent. The aim of the present study was to evaluate the effect of colchicine in the treatment of patients with hepatic fibrosis of various etiologies.