Comparison of the Effects of Hegu Point Ice Massage and 2% Lidocaine Gel on Arteriovenous Fistula Puncture-Related Pain in Hemodialysis Patients: A Randomized Controlled Trial.

There is a paucity of information on the effects of Hegu point ice massage and 2% lidocaine gel on fistula puncture-related pain in hemodialysis patients. The aim of the present research was compare the two methods in terms of their effectiveness. This study is a randomized controlled trial.

Rational design of a novel azoimine appended maleonitrile-based Salen chemosensor for rapid naked-eye detection of copper(II) ion in aqueous media.

Achieving specific selectivity and high sensitivity for the colorimetric recognition of copper(II) ions in aqueous media over a complex background of potentially competing metal ions is inherently challenging in sensor development. Thus, a novel azo-azomethine receptor (L) based on the combination of 2-amino-3-(5-bromo-2-hydroxybenzylamino)maleonitrile and azo-coupled salicylaldehyde scaffold has been designed and synthesized for the naked-eye and rapid detection of Cu(2+) ion at trace level in a wide pH range. Accordingly, the devised chemosensor distinguished Cu(2+) from other metal ions by distinct color change from light yellow to light brown without any expensive equipment.