Publications by authors named "Vaibhavi Vengurlekar"
Article Synopsis
- Circulating tumor cells (CTCs) can indicate cancer recurrence and were studied in patients with large hepatocellular carcinomas (HCC) undergoing preoperative transarterial embolization (TAE).
- The study analyzed blood samples for CTCs and specific miRNA levels before and after TAE to understand their impact on oncological outcomes.
- Results showed varied CTC presence post-surgery, with those who cleared CTCs having better survival, suggesting CTC clearance could be a useful prognostic marker for HCC.
Article Synopsis
- Malignant melanoma in Indian patients frequently shows mutations in key genes of the serine/threonine kinase pathway, particularly BRAF and NRAS, though detailed analyses specific to this population are rare.
- The study analyzed 88 cases of malignant melanoma over eight years, using techniques like Sanger sequencing to identify BRAF alterations in 16.21% of patients and NRAS mutations in 15.7%.
- Results indicated that nodular melanoma is the most common subtype, and further research with larger samples and diverse molecular markers is needed to enhance understanding of melanoma in Indian patients.
Omshree ShettyVikas Ostwal The present study evaluates the mutation pattern and frequency of , and in colorectal carcinoma observed in the tertiary cancer center in India. Consecutive cases of colorectal adenocarcinoma ( = 330) registered from January 2015 to December 2019 (5-year duration) were selected for the study. Molecular analysis for .
View Article and Find Full Text PDF-positive undifferentiated sarcomas are rare. Herein, we present clinicopathological features including immunohistochemical and molecular data, along with the radiological profile of 12 such tumors. Tumors were tested for fusion by reverse transcription polymerase chain reaction (RT-PCR) technique.
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