Publications by authors named "Vahid Tayebi Khorrami"

Today, the applications of natural polysaccharide-based nanofibers are growing in drug delivery and food industries. They also showed their capability as packaging due to biodegradability, mechanical strength, barrier properties, thermal stability, antioxidant, and antimicrobial features. Natural polysaccharides come from different sources, such as plants, microbes, and animals.

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Cancer remains a major global health challenge, and despite available treatments, its prognosis remains poor. Recently, researchers have turned their attention to intelligent nanofibers for cancer drug delivery. These nanofibers exhibit remarkable capabilities in targeted and controlled drug release.

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Objectives: Milk thistle has long been used in the treatment of liver and biliary disorders. In the present study, to make a long-acting delivery system for silibinin (SBN, a major active constituent of milk thistle seeds with antioxidant and hepatoprotective function), mesoporous silica composite nanoparticles (NC) were synthesized and coated with RBC membrane.

Methods: A modified Stöber method was used for NC synthesis, which was then characterized using FE-SEM, DLS, TEM, FTIR, and EDAX techniques.

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