Co-regulated expression of TGF-β Variants and miR-21 in bladder cancer.

Purpose: To investigate a potential alteration in the expression levels of transforming growth factor β (TGF-β) and miR-21 in bladder cancer tissues.

Material And Methods: Using real-time polymerase chain reaction (PCR) method, we examined a potential correlated expression of miR-21 and TGF-β variants in 30 bladder tumors and their marginal/non-tumor biopsy specimens obtained from the same patients.

Results: Our data revealed a significant down-regulation of TGF-β variants (P = .