Surface-Enhanced Raman scattering (SERS) filter paper substrates decorated with silver nanoparticles for the detection of molecular vibrations of Acyclovir drug.

Acyclovir (ACV) drug, a common antiviral agent, is frequently used as the primary clinical treatment method for treating hepatitis B, herpes simplex, and varicella zoster viruses due to its potent therapeutic effect. In patients with compromised immune systems, this medication can stop cytomegalovirus infections, and high doses of this drug are required; however, such prescription leads to kidney toxicity. Therefore, timely and accurate detection of ACV is crucial in many areas.

An ISM approach to overcome the participation barriers in the waste source separation-a case study: Urmia University Campus.

A procedure developed to identify and facilitate the implementation of waste source separation strategies applicable in higher education centers, as a prerequisite for the expansion of recycling programs. The target materials proper to be separated were selected based on quantitative/qualitative analysis of waste produced on the Nazlou Campus of Urmia University, Iran (as a case study). The barriers to implementation of the program were identified using the interpretive structural modeling (ISM) methodology.

A review of applications of surface-enhanced raman spectroscopy laser for detection of biomaterials and a quick glance into its advances for COVID-19 investigations.

Surface-enhanced Raman spectroscopy (SERS) is one of the most sensitive analytical tools. In some cases, it is possible to record a high-quality SERS spectrum in which even a single molecule is involved. Therefore, SERS is considered a significantly promising option as an alternative to routine analytical techniques used in food, environmental, biochemical, and medical analyzes.

New covalent capture probes for imaging and therapy, based on a combination of binding affinity and disulfide bond formation.

We describe the synthesis and development of new reactive DOTA-metal complexes for covalently targeting engineered receptors in vivo, which have superior tumor uptake and clearance properties for biomedical applications. These probes are found to clear efficiently through the kidneys and minimally through other routes, but bind persistently in the tumor target. We also explore the new technique of Cerenkov luminescence imaging to optically monitor radiolabeled probe distribution and kinetics in vivo.