Silica nanoparticles-induced cytotoxicity and genotoxicity in A549 cell lines.

Among the myriad of nanoparticles, silica nanoparticles (SiONPs) have gained significant attention since they are extensively produced and used across several kinds of industries. Because of its widespread usage, there has been increasing concern about the potential health effects. This study aims to evaluate the effects of SiONPs on Interleukin-6 (IL-6) gene expression in human lung epithelial cell lines (A549).

High inflammatory cytokines gene expression can be detected in workers with prolonged exposure to silver and silica nanoparticles in industries.

Occupational health must be strictly considered in industries particularly in nanoparticle factories where workers were exposed to different types of chemicals. We measured the serum levels of inflammatory cytokines in workers who developed skin lesions after exposure to silver and silica nanoparticles. Using a questionnaire in this cross-sectional study, we identified 110 workers in nanoparticle industries who were exposed to silver and silica nanoparticles.

Enhancing catalysis studies with chat generative pre-trained transformer (ChatGPT): Conversation with ChatGPT.

The progress made in natural language processing (NLP) and large language models (LLMs), such as generative pre-trained transformers, (GPT) has provided exciting opportunities for enhancing research across various fields. Within the realm of catalysis studies, GPT-driven models present valuable support in expediting the exploration and comprehension of catalytic processes. This research underscores the significance of ChatGPT in catalysis research, emphasizing its prowess as a valuable tool for furthering scientific inquiries.

Serological and molecular survey of zoonotic visceral leishmaniasis in stray dogs from an endemic focus in Meshkin-Shahr district in Ardabil province, Iran.

Background & Objectives: Visceral leishmaniasis (VL),a protozoan disease caused by Leishmania infantum is a major public health problem and cause of death among infants aged under 1 year and the elderly in endemic foci of Iran. The aim of this study is to determine the status of L.infantum infection in stray dogs from Meshkin-Shahr, a typical endemic area of VL in Iran.

HLA-DRB1 alleles as predisposing and resisting factor in women suffering from vulvovaginal candidiasis.

Background: Vulvovaginal candidiasis (VVC) is a vaginal mucosal infection that usually affects women in their reproductive age. When the signs of VVC persist on a daily basis or last for a long time and repeat at least three times per year, the disease is considered chronic and recurrent.

Objective: The purpose of this study was to evaluate the frequency of HLA-DRB1 alleles in patients with recurrent vulvovaginal candidiasis (RVVC).

Fabrication of moiré on curved surfaces.

Moiré is an appealing visual effect observable when two or more repetitive patterns are superposed. Fabrication of moiré effects has already proven to be useful in a range of applications, from art to engineering. Here, we introduce a method for designing and fabricating level-line moirés on curved surfaces.

Investigating the expression of ALS2 and ALS9 genes along with allele frequency of ALS9 in patients with vulvovaginal candidiasis.

Background: Vulvovaginal candidiasis (VVC) is a vaginal mucosal infection that usually infects women in their reproductive age. When the signs of VVC persist on a daily basis or last for a long time and repeat at least three times per year, the disease is considered chronic and recurrent.

Objectives: The purpose of this study was to determine the expression rate of 2 genes responsible for adhesion and virulence of candida in RVVC patients using Real-time PCR, and comparing them together and assess the presence or absence of ALS9-2 allele in these patients.

Filaggrin gene polymorphisms in Iranian ichthyosis vulgaris and atopic dermatitis patients.

Background: Filaggrin is a key structural epidermal protein in terminal differentiation and formation of skin barrier. The important role of filaggrin and its effects in various cutaneous and noncutaneous disorders initiated a cascade of considerable research in recent years. Loss-of-function mutations in FLG, the human gene encoding profilaggrin/filaggrin, is the cause of the common skin condition ichthyosis vulgaris (IV) and major genetic predisposing factor for atopic dermatitis (AD).

Mutation analysis of Phenylalanine hydroxylase gene in Iranian patients with Phenylketonuria.

Phenylketonuria as the most common genetic metabolic disorder is the result of disruption of the phenylalanine hydroxylase gene. This study was carried out to explore the phenylalanine hydroxylase gene mutation status of Iranian phenylketonuria patients. Blood samples were collected from 30 patients, and hot spot areas of the phenylalanine hydroxylase gene, including exons 6, 7, 8, 11, and 12 were studied through polymerase chain reaction and sequencing techniques.

FabSquare: Fabricating Photopolymer Objects by Mold 3D Printing and UV Curing.

The FabSquare system is a personal fabrication method that lets users fabricate objects by molding photopolymers inside a 3D printed mold. The molds are printed with UV-transparent materials that allow for UV curing--the polymerization and solidification of the fluid content. The molds can be repeatedly reused to fabricate identical objects or create new objects with identical geometry, but different components.

Mutation characterization and heterodimer analysis of patients with leukocyte adhesion deficiency: Including one novel mutation.

Background And Aim: Leukocyte adhesion deficiency type 1 (LAD-I) is a rare, autosomal recessive disorder of neutrophil migration, characterized by severe, recurrent bacterial infections, inadequate pus formation and impaired wound healing. The ITGB2 gene encodes the β2 integrin subunit (CD18) of the leukocyte adhesion cell molecules, and mutations in this gene cause LAD-I. The aim of the current study was to investigate the mutations in patients diagnosed with LAD-I and functional studies of the impact of two previously reported and a novel mutation on the expression of the CD18/CD11a heterodimer.

N -Ink Printer Characterization With Barycentric Subdivision.

Printing with a large number of inks, also called N -ink printing, is a challenging task. The challenges comprise spectral modeling of the printer, color separation, halftoning, and limitations of the amount of inks. Juxtaposed halftoning, a perfectly dot-off-dot halftoning method, has proved to be useful to address some of these challenges.

Treatment of 100 chronic thalassemic leg wounds by plasma-rich platelets.

Objective: Thalassemia is a heterogeneous group of congenital hemoglobinopathies caused by mutations in the globin gene complex that result in an unbalanced globin synthesis. Unmatched globin chains bind to the cytosolic surface of red blood cell membrane where they cause oxidative damage that might in part be responsible for membrane weakness. The deformability of red blood cells and hypercoagulable state in thalassemic patients have been incriminated in leg ulcer formation, as this might cause ischemia to the skin and consequently friability and ulceration.

Juxtaposed color halftoning relying on discrete lines.

Most halftoning techniques allow screen dots to overlap. They rely on the assumption that the inks are transparent, i.e.