Oncocytic Carcinoma Ex-Pleomorphic Adenoma of the Lacrimal Gland.

Oncocytic carcinoma is a rare malignant neoplasm of oncocytic cells, such cells being characterized by abundant granular eosinophilic cytoplasm, invasive growth, and pronounced cellular pleomorphism. It may arise de novo, or through malignant transformation of a pre-existing benign oncocytoma. Oncocytic carcinoma most commonly occurs in the salivary glands, with rare involvement of the ocular adnexa where it mainly affects caruncle, conjunctiva, and lacrimal sac, and only very arises in the lacrimal gland.

Dacryoscintillography in Patients With Symptomatic, but Patent, Lacrimal Drainage Systems.

Purpose: To relate dacryoscintillographic features to presenting symptoms and signs for watery-eyed patients with patent drainage systems.

Methods: Retrospective case note and imaging review for patients with watering eye(s) and clinical evidence of impaired tear drainage who underwent dacryoscintillography (DSG). Three DSG features were graded, along with 4 symptoms, 7 signs, and the degree of fluid reflux and nasal fluid passage on gentle syringing.

Presentation of Orbital Metastases.

Purpose: To compare clinical characteristics of patients with and without a known systemic malignancy at the time of diagnosis of orbital metastases.

Methods: Retrospective case note and imaging review for patients with orbital metastases presenting between 1980 and 2022. Patients were classified as having known malignancy at orbital presentation (group I) or without known malignancy (group II).

Clinical Characteristics of Patients With Symptomatic Nasolacrimal Duct Stenosis.

Purpose: To characterize symptoms and signs for patients with tearing eye(s) and ipsilateral nasolacrimal duct stenosis (NLDS), as defined by delayed fluorescein disappearance test and ocular reflux of saline during gentle irrigation of a patent drainage system.

Methods: Retrospective case-note review of a consistent grading of 4 symptoms and 7 signs, together with estimates of the degree of fluid reflux and nasal fluid passage on gentle saline syringing. Characteristics, including gender differences, were compared for unilateral or bilateral symptoms.

Presentation of Spontaneous Orbital Hemorrhage.

Purpose: To evaluate the presenting features of patients with nontraumatic orbital hemorrhage (NTOH) based on etiopathological factors.

Methods: A retrospective case-note review for demographics and presenting features of patients with nontraumatic orbital hemorrhage. Patients were categorized into 3 groups: group I with known systemic vascular disease, group II with known or newly revealed orbital vascular anomalies, and group III with no known underlying vasculopathy.

Long-Term Outcome for Primary Papillomas of the Lacrimal Drainage System.

Purpose: To report long-term outcomes after surgery for primary benign papillomas of the lacrimal drainage system.

Methods: Retrospective review of patients with primary lacrimal drainage system papillomas, first seen between 1984 and 2021, but excluding lesions with sino-nasal origin or malignant histology. Patients were categorized by tumor histology (squamous, transitional, and mixed cell) and growth pattern (exophytic, endophytic, or mixed).

Repeated Lacrimal Gland Biopsies.

Purpose: To examine the indications for repeated lacrimal gland biopsies, and the rate of detection of a new diagnosis.

Methods: A single-center, retrospective review of patients who underwent more than 1 lacrimal gland biopsy, either ipsilateral or contralateral, between 2000 and 2022.

Results: One hundred and twenty-three patients (80 female; 65%) had repeated lacrimal gland biopsy.

One-stage Intraconal Volume Modification for Exposed and Nonexposed Ball Implants.

Purpose: To assess long-term outcomes and reinterventions for exposed and nonexposed intraconal orbital implants after single-stage socket revisional surgery.

Methods: Retrospective case-note review of patients with exposed or nonexposed orbital ball implants, who underwent a single-stage ball exchange (Group I) or ball removal with dermis-fat graft (Group II); Group I was subdivided as having either exposed (A) or nonexposed (B) implants. Outcomes were compared with similar cohorts undergoing multistage surgery.

Long-Term Outcome of Staged Socket Surgery for Acquired Anophthalmos.

Purpose: To evaluate long-term outcomes of staged volume rehabilitation for acquired anophthalmos.

Methods: Case-note review of patients who had preceding i) eye removal without implant, ii) eye removal with an intraconal implant, but ball-related problems, or iii) removal of exposed implant. Secondary interventions were a) a first-time ball implant, b) dermis-fat graft, c) ball repositioning, d) ball replacement after prior removal, or e) orbital floor implantation.

Horizontal eyelid shortening alone versus combined procedures for the correction of involutional lower eyelid entropion.

Background: Conventionally, management of involutional entropion involves correcting both vertical and horizontal laxity, however the optimal surgical approach is debated.

Objective: To compare the recurrence rate of horizontal lower eyelid shortening alone with combined surgical approaches for correction of involutional lower eyelid entropion.

Methods And Material: A retrospective, comparative, consecutive case series of patients undergoing surgery for involutional lower eyelid entropion with both horizontal and vertical laxity.

Recurrent superior orbital fissure syndrome associated with VEXAS syndrome.

Purpose: To describe a case of recurrent orbital inflammation and superior orbital fissure syndrome associated with VEXAS (vacuoles, E1 enzyme, X-linked, auto-inflammatory, somatic) syndrome.

Case Presentation: VEXAS syndrome is a recently identified multi-system inflammatory disease of late adult onset. The authors describe the case of a 76-year-old man who presented with recurrent episodes of orbital inflammation, with superior orbital fissure syndrome, dacryoadenitis and orbital myositis.

Orbital infarction during drug abuse: tissues of the globe do not appear to recover function.

Aim: To describe the features of an orbital infarction syndrome arising after prolonged orbital pressure during drug-induced stupor in young people.

Patients And Methods: The clinical presentation and course for drug-induced orbital infarction is described, based on a retrospective review of clinical notes and imaging.

Results: Two cases of orbital infarction syndrome, due to prolonged orbital compression caused by sleeping with pressure on the orbit during drug-induced stupor, are described.

Long-Term Surgical Outcome for Orbital Solitary Fibrous Tumors.

Purpose: To report long-term outcomes after surgery for orbital solitary fibrous tumors.

Methods: Retrospective review of patients with orbital solitary fibrous tumor, first seen between 1971 and 2022. Primary excisions were grouped as (A) surgically intact, (B) macroscopic, but with cell spillage, or (C) known incomplete excision.

Presentation of orbital solitary fibrous tumours.

Aims: To evaluate presenting features of patients with orbital solitary fibrous tumours (SFTs), based on histological phenotype.

Methods: A retrospective case-note review was performed for demographics and presenting features for patients with orbital SFTs. The tumours were classified as "Group IA" hypocellular SFT phenotype, "Group IB" haemangiopericytoma phenotype and low mitotic activity, and high-grade "Group II" haemangiopericytoma phenotype with high mitotic activity.

Incidence and Risk Factors for Poor Postoperative Visual Outcome After Excision of Orbital Cavernous Venous Malformations.

Aims: To determine the incidence and risk factors for poor postoperative visual outcome (PPVO) after removal of orbital cavernous venous malformations (OCVMs).

Methods: Retrospective case-note and imaging review for patients undergoing excision of OCVMs, with estimation of odds-ratios (ORs) and relative risks (RRs) for visual loss in relation to the position of the mass, surgical approach, and patient factors.

Results: The 290 patients (179 female; 62%) presented at a mean age of 46.

Necrotizing Blepharoconjunctivitis and Keratitis in Human Monkeypox.

Importance: Ophthalmic manifestations occur in less than 5% of patients with human mpox (monkeypox), most commonly presenting with self-limiting conjunctivitis and keratitis. Cases with severe ophthalmic complication are uncommon.

Objective: To present a case of human mpox with sight-threatening necrotizing blepharoconjunctivitis.

Chorio-Retinal Folds Associated With Orbital Cavernous Venous Malformations.

Purpose: To determine the incidence of clinically detectable chorio-retinal folds (CRFs) with orbital cavernous venous malformations (OCVMs) and their recovery.

Methods: Retrospective case-note and imaging review, with estimation of odds ratios in relation to the position and volume of the mass.

Results: Records for 402 patients were reviewed, 83 (21%) having CRFs.

Ophthalmic Presentation and Outcome for Sinonasal Mucoceles.

Purpose: The purpose of this study was to evaluate ophthalmic features and outcomes for patients who present with sinonasal mucoceles expanding into the orbit.

Patients And Methods: Retrospective chart review for patients seen in a specialist orbital clinic over 25 years, with a review of demographics, clinical characteristics, imaging features, and outcomes after treatment.

Results: Sixty patients (38 males; 63%) presented at a mean age of 51 years (range 3-89).