Publications by authors named "Vagionis A"

Purpose: Optimal laser settings during endoscopic stone disease management still represents a debatable issue. The aim of this systematic review is to summarize all existing evidence regarding the comparison of high-power (HP) versus low-power (LP) laser settings during different endoscopic lithotripsy procedures.

Methods: PubMed, Scopus and Cochrane databases were systematically screened, based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Guidelines.

View Article and Find Full Text PDF
Article Synopsis
  • This study investigated the effects of different irrigation setups and ureteral access sheath sizes on intrarenal pressure during flexible ureteroscopy in pigs.
  • Utilizing anesthetized female pigs and a flexible ureteroscope that recorded pressure, the researchers performed procedures with varying irrigation methods (gravity vs. manual pumping) and UAS sizes (11/13 and 12/14).
  • Results showed significantly lower intrarenal pressure with the use of UAS and under various irrigation methods, indicating the potential for improved surgical outcomes through real-time pressure monitoring during ureteroscopy.
View Article and Find Full Text PDF

Inflatable penile prosthesis (IPP) surgery is an effective treatment for erectile dysfunction (ED), but infections pose a significant threat to its success. Current guidelines lack antifungal recommendations, despite rising fungal infection rates post-IPP surgery. This review examines epidemiology, risk factors (including diabetes mellitus, immunosuppression, and obesity), and pathogenesis, highlighting the role of biofilm formation in device contamination.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to assess the effectiveness and safety of using high-power Holmium: Yttrium-Aluminum-Garnet (Ho:YAG) lasers over 100 W for bladder stone treatment.
  • An experimental setup involved testing on artificial stones and porcine bladder, while a clinical trial was conducted on 35 patients with various laser power settings.
  • Results showed a 100% stone-free rate in patients, faster ablation rates with high power, and minimal complications, indicating that Ho:YAG laser lithotripsy is a safe and efficient method for treating bladder stones.
View Article and Find Full Text PDF

Objective: In this review, we investigated the current literature to find out which artificial stones (AS) are available in endourology, and in which experimental and training schemes they are used.

Materials And Methods: A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Twenty-one out of 346 studies met our inclusion criteria and are presented in the current review.

View Article and Find Full Text PDF

Purpose: The aim of this study is the evaluation of the distribution of paclitaxel (PTX) released by a coated balloon in the layers of rabbit's urethra.

Methods: 18 rabbits were included. A laser device was used for the stricture formation.

View Article and Find Full Text PDF

Objective: Transurethral resection of bladder tumor is one of the most common everyday urological procedures. This kind of surgery demands a set of skills that need training and experience. In this review, we aimed to investigate the current literature to find out if simulators, phantoms, and other training models could be used as a tool for teaching urologists.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to assess the learning curve for four basic surgical skills in both laparoscopic and robotic surgeries using the avatera® system.
  • Participants, who had no prior experience, practiced tasks after watching educational materials and undergoing 2-hour training, with their performance times measured across multiple attempts.
  • Results showed that practice significantly reduced completion times, and prior laparoscopic experience enhanced training efficiency, indicating that robotic skills can be learned more quickly than laparoscopic ones.
View Article and Find Full Text PDF

Purpose: To evaluate the safety and feasibility of partial nephrectomy with the use of the novel robotic system in an in vivo animal model.

Methods: Right partial nephrectomy was performed in female pigs by a surgical team consisting of one surgeon and one bedside assistant. Both were experienced in laparoscopic surgery and trained in the use of the novel robotic system.

View Article and Find Full Text PDF

Background: Robot-assisted radical prostatectomy is a minimally invasive, safe procedure preferred in the management of localized prostate cancer. In this study, we present our initial experience with the avatera system (avateramedical GmbH, Jena, Germany) in robot-assisted radical prostatectomy.

Methods: A total of fourteen patients underwent robot-assisted radical prostatectomy using this newly introduced system in our department from June 2022 to October 2022.

View Article and Find Full Text PDF
Article Synopsis
  • The study assesses the safety and feasibility of the Florence robotic intracorporeal neobladder technique during laparoscopic radical cystectomy in patients with muscle-invasive bladder cancer.
  • All surgeries were completed successfully with a median operative time of 343 minutes, no intraoperative complications, and a hospital stay averaging 7 days, demonstrating effective short-term outcomes.
  • While some patients experienced minor complications, the overall results indicate that this technique is promising, but further large-scale prospective studies are needed to confirm long-term effectiveness.
View Article and Find Full Text PDF

Objective: To evaluate the tissue injury caused by the force applied by the roboticassisted graspers of avatera robotic surgical system on bowel tissue.

Methods: An experimental in vivo porcine model with 1 pig was conducted. After a standard transperitoneal setup of the avatera robotic surgical system, different laparoscopic and robotic graspers were used on the bowel with maximum force applied each time.

View Article and Find Full Text PDF

Purpose: This pilot study was designed to interpret the technically specific features of the avatera robotic system and present our initial experience with this novel platform in robot-assisted pyeloplasty (RAP).

Methods: A single-center prospective study was conducted including all patients who underwent RAP with the avatera robotic system from June 2022 to October 2022 in our Department. Transperitoneal robot-assisted dismembered pyeloplasty was performed in all cases.

View Article and Find Full Text PDF

Objective: To evaluate the transfer of the practical skills of robot-assisted surgery acquired in the dry-lab into a real live experimental setting for performing upper and lower urinary tract surgeries.

Material And Methods: An in vivo experimental study design was utilized. Six urology trainees and fellows; two 2nd year trainees with no previous exposure to laparoscopic surgery (Group 1), two 4th year residents with medium exposure to laparoscopic surgery (Group 2) and two fellows trained to perform laparoscopic surgeries (Group 3) performed ureteral reimplantation into the bladder, pyeloplasty, and radical nephrectomy on three female pigs under general anesthesia.

View Article and Find Full Text PDF

Percutaneous nephrolithotomy (PCNL) is the gold standard of treatment for large renal calculi. Papillary puncture is the mainstay of treatment for large renal calculi, but the non-papillary has been introduced and gained some interest. The aim of this study is the investigation of trends of non-papillary access for PCNL over the years.

View Article and Find Full Text PDF

Introduction: The high-power holmium: yttrium-aluminum-garnet lasers provide a wide variety of settings for stone disintegration. The aim of this study is to evaluate the effect of short and long pulse duration on ablation rates on urinary stones.

Materials And Methods: Two types of artificial stones were created by BegoStone™ with different compositions (15:3 and 15:6, stone/water ratio).

View Article and Find Full Text PDF

Introduction: The aim of this study was to evaluate the possible histopathological alterations that occur in the kidneys due to a continuous temperature increase above 43°C for one hour of lithotripsy using a newly introduced thulium fiber laser (TFL).

Material And Methods: Two female pigs were used. After the insertion of a 9.

View Article and Find Full Text PDF

Purpose: To investigate the feasibility of the avatera system for performing robot-assisted radical cystectomy (RARC) followed by intracorporeal reconstruction of ileal neobladder.

Methods: Six anesthetized female pigs were used to perform RARC and formation of the intracorporeal orthotopic ileal neobladder. Three surgeons with different level of expertise in the use of robotic systems performed RARC after a short instructional lecture and a 2-h hands-on training.

View Article and Find Full Text PDF

To evaluate the feasibility and intraoperative technical parameters of the new robot-assisted surgical system Avatera by performing bilateral nephrectomy in a live porcine model. Six pigs underwent bilateral robot-assisted radical nephrectomy using the Avatera robotic system (RS). The operations were performed by experienced open (Group 1) and laparoscopic (Group 2) surgeons.

View Article and Find Full Text PDF

Objective: To investigate the effect of the diameter of laser fiber, pelvis volume, presence and type of the stone on irrigation fluid temperature rise.

Material And Methods: A 20ml syringe, 12/14 ureteral access sheath(UAS), a dual-lumen catheter and a thermocouple were used.  The 12/14Fr UAS(Cook Ireland Ltd.

View Article and Find Full Text PDF

Purpose: Based on the current trend of miniaturization of instruments used in percutaneous nephrolithotomy (PCNL), it is necessary to compare different PCNL modalities regarding their access sheath size used. Thus, the safety and efficacy among standard, mini and ultra-mini PCNL (s-PCNL, m-PCNL, um-PCNL) were compared.

Methods: We performed a prospective, non-randomized trial between January 2018 and July 2020.

View Article and Find Full Text PDF

Purpose Of Review: The aim of this study was to present the recent and promising innovations of the new laser technologies used for the treatment of renal stones.

Recent Findings: Taking advantage of pulse modulation, new technologies such as the Moses effect, the Virtual basket and the Vapor tunnel have been introduced. These technologies seem to improve lithotripsy efficacy by reducing retropulsion and increasing the stone ablation rate.

View Article and Find Full Text PDF

Purpose: To investigate the effect of prolonged laser activation on irrigation fluid temperature by varying the power settings flow rate (10-30 ml/min).

Materials And Methods: An experimental study using a 20 ml syringe, 12/14 ureteral access sheath, a dual-lumen catheter and a thermocouple was performed. The laser was fired with 12 W (0.

View Article and Find Full Text PDF

Purpose: To investigate the effect of different combinations of laser power settings and irrigation conditions using the pulse modulation technology of Quanta™ on irrigation fluid temperature (IFT) during FURS (flexible ureteroscopy) on an in-vivo porcine model with artificial stones.

Materials And Methods: A female pig was used. Following the insertion of artificial stones (Begostone™, BEGO USA, Lincoln, RI), a K-type thermocouple was fixed to the created percutaneous access tract.

View Article and Find Full Text PDF

Purpose Of Review: The purpose of current systematic review and meta-analysis is to determine the efficacy and safety of the administration of tranexamic acid in patients undergoing PCNL. The study was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement. This systematic review and meta-analysis includes randomized comparative prospective studies.

View Article and Find Full Text PDF