Publications by authors named "Vagelis Georgiu"
Article Synopsis
- Fetal smoke exposure is a significant and avoidable risk factor for complications during birth and can contribute to childhood obesity, with varying risks based on maternal and paternal smoking behavior.
- A comprehensive analysis was conducted involving 229,158 families from 28 cohorts across Europe and North America, examining how different patterns of smoking (quitting or reducing, and maternal vs. paternal smoking) affect birth outcomes.
- Results indicated that maternal smoking during the entire pregnancy increases the risks of preterm birth, small size for gestational age, and childhood overweight, while smoking only in the first trimester raised the risk of childhood overweight without adverse effects on birth outcomes.
Importance: Both low and high gestational weight gain have been associated with adverse maternal and infant outcomes, but optimal gestational weight gain remains uncertain and not well defined for all prepregnancy weight ranges.
Objectives: To examine the association of ranges of gestational weight gain with risk of adverse maternal and infant outcomes and estimate optimal gestational weight gain ranges across prepregnancy body mass index categories.
Design, Setting, And Participants: Individual participant-level meta-analysis using data from 196 670 participants within 25 cohort studies from Europe and North America (main study sample).
Article Synopsis
- Maternal obesity and excessive weight gain during pregnancy are linked to increased risks of childhood overweight and obesity, with effects strongest during late childhood.
- A large study analyzed data from over 162,000 mothers and their children across multiple countries to assess these associations using advanced statistical methods.
- Results indicate that both pre-pregnancy BMI and gestational weight gain significantly contribute to childhood obesity, suggesting the need for targeted interventions during pregnancy to address these risks.
Background: Gestational weight gain differs according to pre-pregnancy body mass index and is related to the risks of adverse maternal and child health outcomes. Gestational weight gain charts for women in different pre-pregnancy body mass index groups enable identification of women and offspring at risk for adverse health outcomes. We aimed to construct gestational weight gain reference charts for underweight, normal weight, overweight, and grades 1, 2 and 3 obese women and to compare these charts with those obtained in women with uncomplicated term pregnancies.
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