[Characteristics of hormonal homeostasis in children with thymus enlargement syndrome].

Hormonal homeostasis was examined in 104 children aged 1 to 14 years with thymus enlargement. There was a significant growth of somatotropic hormone in children of the first 3 years of life, characterized by thyroid dysfunction and hypofunction increase with age, by a tendency towards ACTH and hydrocortisone lowering under 6 years of age, and a significant decrease of those parameters in children over 6 years. The children with thymus enlargement also showed other disorders of hormonal homeostasis.

[Anti-measles humoral immunity in children with thymus hyperplasia].

Analysis is made of the data obtained during clinical studies of the vaccinal process in 54 children with grades I-II thymus enlargement, vaccinated against measles. The clinical course of the vaccinal process in these children does not differ from the common course in normal children vaccinated against measles. The children with grades I-II thymus enlargement are capable of producing humoral antiviral immunity and of preserving high titres of antiviral antibodies for a long time.

[Vaccination against diphtheria and tetanus of children with thymus hyperplasia syndrome].

Inhibition of cellular and humoral immunity was established in children with grade I thymus enlargement syndrome (TES). The most pronounced changes were recorded in children aged 1-5 years. Vaccination against diphtheria and tetanus performed before the diagnosis of the TES was made were followed by satisfactory output of anatoxins, indicating the prospectiveness of the vaccination of the given children's group with DPT vaccine and DT- and DT-M-anatoxin.