Publications by authors named "Vafa Fakhri"

Polyesters based on polyols have emerged as promising biomaterials for various biomedical applications, such as tissue engineering, drug delivery systems, and regenerative medicine, due to their biocompatibility, biodegradability, and versatile physicochemical properties. This review article provides an overview of the synthesis methods, performance, and biodegradation mechanisms of polyol-based polyesters, highlighting their potential for use in a wide range of biomedical applications. The synthesis techniques, such as simple polycondensation and enzymatic polymerization, allow for the fine-tuning of polyester structure and molecular weight, thereby enabling the tailoring of material properties to specific application requirements.

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As a glycerol-based polyester, poly(glycerol azelaic acid) (PGAz) has shown great potential for biomedical applications, such as tissue engineering. However, it tends to show low mechanical strength and a relatively fast biodegradation rate, limiting its capability of mimicking and supporting a broad range of hard tissues such as bone. Moreover, the typical thermal curing process of poly(glycerol--diacids) is one of their drawbacks.

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Nanocomposites containing clay nanoparticles often present favorable properties such as good mechanical and thermal properties. They frequently have been studied for tissue engineering (TE) and regenerative medicine applications. On the other hand, poly(glycerol sebacate) (PGS), a revolutionary bioelastomer, has exhibited substantial potential as a promising candidate for biomedical application.

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Eco-friendly nanocomposite aerogels were prepared as adsorbents for the removal of a model pollutant (methylene blue, MB) from water. These aerogels were comprised of hydroxyapatite (HA) nanoparticles embedded within a polymer matrix consisting of a semi-interpenetrating network of xanthan gum (XG) and polyacrylic acid (PAA). Microscopy and BET analysis showed that the aerogels formed had a nanofibrous porous microstructure with a surface area of 89 m/g.

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As a consequence of industrial activities, one of the most prevalent components in wastewater is Water-soluble dyes needed to be removed. In this research, eco-friendly adsorbents based on poly(glycerol sebacate) (PGS), including PGS-graphene oxide nanoparticles (GO), PGS-graft-chitosan(CS), and PGS-CS-GO nanocomposites, have been proposed as efficient dye adsorbents for the wastewater treatment procedure. FESEM images showed that a smooth and uniform structure was created over incorporating CS into PGS.

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