Publications by authors named "Vaclav Safka"
Objective: The article deals with occupational health protection and identification of health risks in the work environment of the Ministry of Defence (MoD) of the Czech Republic (CR). It focuses on the assessment of the incidence of occupational diseases (OD) in high-risk and risk-free occupational categories in the years 2010-2019 and compares them with data from the civilian sector. It identifies the differences between military staff and civilian employees of the MoD.
View Article and Find Full Text PDFObjectives: The aim of this work is to compare the current prevalence of selected risk factors in cardiovascular diseases in the Czech general population in a particular region with a selected population of Czech soldiers in a particular military unit.
Methods: Within medical preventive examinations, data from 684 civilians aged between 30-60 years were obtained (405 men and 279 women). Within compulsory medical preventive examinations, data from 659 soldiers from a particular military unit aged between 30-60 years were obtained (576 men and 83 women).
Abundant drinking of fluids at any occasion became popular in wealthy society in last decades. It is referred to asserted beneficial health effects, but rationale of these recommendations is disputed in expert environment as hardly traceable and tenable. Authors of the article analyse theoretical issues as well as empiric literary evidence for the current popular recommendation.
View Article and Find Full Text PDFObjectives: The aim of the study is to describe current prevalence of selected risk factors in the Czech general population in a particular region and to compare the data with recently published results in the selected population of Czech soldiers. The work also deals with the advantages and disadvantages of methods determining overweight and obesity.
Methods: Within medical preventive examinations the data of 1,051 individuals (482 men, 569 women) were obtained.
Unlabelled: Introduction and Aim: Hepatic encephalopathy (HE) is a common complication of transjugular intrahepatic portosystemic shunting (TIPS). It is associated with a reduced quality of life and poor prognosis. The aim of this study was to compare two groups of patients who did and did not develop overt HE after TIPS.
View Article and Find Full Text PDFBackground: Budd-Chiari Syndrome (BCS) is characterized by obstruction of blood flow in hepatic veins. The aim of the study was to analyze diagnosis, etiology and management of BCS.
Methods: We analyzed 44 patients (32 females, 12 males, the mean age <35y of age) treated with TIPS.
Article Synopsis
- The study compared two iron chelators, dexrazoxane (DEX) and deferoxamine (DFO), to evaluate their effects on acute liver injury caused by lipopolysaccharide (LPS) in rats.
- While both chelators reduced liver iron content, only DFO showed protective effects against liver injury, whereas DEX worsened oxidative stress indicators.
- The findings suggest significant differences in how these chelators affect liver impairment, highlighting the importance of specific properties in chelation therapy.
Glycogen phosphorylase BB levels are associated with haemodynamic parameters in cirrhotic patients undergoing transjugular intrahepatic portosystemic shunt insertion.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub
September 2015
Background: Transjugular intrahepatic portosystemic shunts (TIPS) have become a widely accepted tool in the treatment of patients with symptomatic portal hypertension. The aim of our study was to assess glycogen phosphorylase BB (GPBB) concentration in relation to echocardiographic and haemodynamic parameters in patients before and after TIPS insertion.
Methods: The study population consisted of 55 patients (38 men and 17 women, age 55.
Introduction: Liver cirrhosis is associated with hyperdynamic circulation which can result in heart failure. Transjugular intrahepatic portosystemic shunt (TIPS) due to increase of cardiac output is a stressful stimulus for cardiovascular system. Therefore, new methods for early detection of heart failure are needed.
View Article and Find Full Text PDFBackground: Transjugular intrahepatic portosystemic shunts (TIPSs) have become a widely accepted tool in the treatment of patients with symptomatic portal hypertension. The aim of our study was to assess the value of cardiac markers before and after TIPS insertion for the prediction of one-year mortality in cirrhotic patients.
Methods: The study population consisted of 55 patients (38 men and 17 women, aged 55.
Purpose: To evaluate the effects of secondary deployment of expanded polytetrafluoroethylene (ePTFE)-covered stent grafts in the treatment of dysfunctional transjugular intrahepatic portosystemic shunts (TIPSs) in comparison with other common approaches (conventional angioplasty or implantation of bare metal stents).
Materials And Methods: A retrospective review of 121 dysfunctional bare metal TIPS presenting between 2000 and 2004 was conducted. The group was divided into four subgroups according to the type of intervention: conventional angioplasty (52 cases; 43%), bare metal stent deployment (35 cases; 28.
Background/aims: Postparacentesis circulatory dysfunction is the most severe complication of ascites paracentesis. The aim of our study was to compare the standard treatment with the administration of a vasoconstrictor terlipressin.
Methodology: Forty-nine patients treated by paracentesis due to tense ascites were randomized for the treatment with albumin (8g/L of removed ascites) or terlipressin (1 mg every four hours for 48 hours).
Background/aims: The main problem of transjugular intrahepatic portosystemic shunt is high incidence of hepatic encephalopathy (HE). The aim of our retrospective study was to determine the incidence the risk factors of clinically significant encephalopathy.
Methodology: 430 patients with liver cirrhosis treated by TIPS in Faculty Hospital in Hradec Králové, Czech Republic.